Results 51 to 60 of about 94,745 (265)
Simulating brain-scale networks digitally is often hindered by extensive memory access. In this context, using low-precision data types and more efficient models to represent state variables is a viable alternative to improve the scalability of the ...
Pablo Urbizagastegui +2 more
doaj +1 more source
Digital filter optimization for C language
A method for transforming C code with floating-point values into C code with integer variables is developed. The objective is to avoid any operations with floating-point data types, thereby increasing the execution speed of the program on a ...
BARLEANU, A., BAITOIU, V., STAN, A.
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
[Objectives] In order to improve the standards of the anti-shock assessment testing of shipboard equipment, [Methods] the shock response data of the low-frequency vibration of a 200-ton floating shock platform is analyzed.
ZHANG Lei +5 more
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
FPU-Supported Running Error Analysis
A-posteriori forward rounding error analyses tend to give sharper error estimates than a-priori ones, as they use actual data quantities. One of such a-posteriori analysis – running error analysis – uses expressions consisting of two parts; one generates
T. Zahradnický, R. Lórencz
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Accuracy in floating-point computations is critical for reliable software, especially in systems where precision impacts safety and performance. Inaccuracies from rounding errors and precision loss can lead to significant issues in applications like ...
M. G. Thushara, K. Somasundaram
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Robustness Analysis of Floating-Point Programs by Self-Composition
Robustness is a key property for critical systems that run in uncertain environments, to ensure that small input perturbations can cause only small output changes.
Liqian Chen +4 more
doaj +1 more source

