Results 151 to 160 of about 4,310 (263)

Controlling Dynamical Systems Into Unseen Target States Using Machine Learning

open access: yesAdvanced Intelligent Systems, EarlyView.
Parameter‐aware next‐generation reservoir computing enables efficient, data‐driven control of dynamical systems across unseen target states and nonstationary transitions. The approach suppresses transient behavior while navigating system collapse scenarios with minimal training data—over an order of magnitude less than traditional methods.
Daniel Köglmayr   +2 more
wiley   +1 more source

Methylophiopogonanone a attenuates pulmonary fibrosis by inhibiting SPP1‐mediated macrophage polarization via the PI3K/Akt pathway

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Transcriptome sequencing identified secreted phosphoprotein 1 (SPP1) as a crucial target through which methylophiopogonanone A (MOA) ameliorates pulmonary fibrosis. Molecular docking and microscale thermophoresis (MST) assays confirmed a favorable binding affinity between MOA and SPP1.
Fan Yang   +10 more
wiley   +1 more source

Hematoma Interleukin‐1 Receptor Antagonist Concentrations Predict Long‐Term Outcome in Acute Human Intracerebral Hemorrhage

open access: yesAnnals of Neurology, EarlyView.
Objectives The interleukin (IL)‐1, IL‐6, and C‐reactive protein (CRP) pathway is central to the immune response after intracerebral hemorrhage (ICH). We tested for associations between hematoma and plasma cytokine concentrations and patient outcomes in Minimally Invasive Surgery Plus Rt‐PA for ICH Evacuation Phase III (MISTIE III) participants ...
Adrian R. Parry‐Jones   +54 more
wiley   +1 more source

A distinct lineage pathway drives parvalbumin chandelier cell fate in human interneuron reprogramming. [PDF]

open access: yesSci Adv
Stamouli CA   +11 more
europepmc   +1 more source

In utero exposure to anti-Caspr2 antibody disrupts parvalbumin interneuron function in the hippocampus. [PDF]

open access: yesBrain Behav Immun
Bagnall-Moreau C   +5 more
europepmc   +1 more source

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