Results 91 to 100 of about 41,220 (298)
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak+14 more
wiley +1 more source
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan+10 more
wiley +1 more source
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim+8 more
wiley +1 more source
Searching for semifield flocks
In the projective space \(PG(3,q)\) let \(K\) be a quadratic cone with vertex \(v\) ; a flock \(\mathcal {F}\) of \(K\) is a set of \(q\) disjoint conics partitioning \ \(K \setminus \{ v \}\). The interest in flocks is due to their links with many geometric objects. For instance a spread (i.e.
openaire +2 more sources
Modeling of Avian Influenza Mitigation Policies within the Backyard Segment of the Poultry Sector
This study presents a conceptual model for the analysis of avian influenza mitigation options within the small poultry farm sector (backyard flocks). The proposed model incorporates epidemiological susceptible-infected-recovered (SIR) methodology into an
Levan Elbakidze
doaj +1 more source
THE OPTIMUM STRUCTURE OF BREEDING FLOCKS. II. METHODS OF DETERMINATION [PDF]
Everett R. Dempster, I. Michael Lerner
openalex +1 more source
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka+10 more
wiley +1 more source
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu+15 more
wiley +1 more source