Results 121 to 130 of about 41,220 (298)
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Poultry Science, 2020 : There is increasing evidence that health and performance of the breeder flock significantly contributes to health and performance of their progeny.
Ingrid C. de Jong, Johan W. van Riel
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Intra-Flock Genetic Merit under Floor and Cage Managements
, 1956 Dorothy C. Lowry +2 more
openalex +1 more source
Territorial Behaviour in Flocks of Domestic Fowls [PDF]
, 1962 G. McBride, F. Foenander
openalex +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Death and reproductive rates of Sheep in relation to flock culling and selection [PDF]
, 1960 F. Hickey
openalex +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Avitaminosis A in Commercial Poultry Flocks
, 1941 Max Rubin, H.R. Bird, H.M. DeVolt
openalex +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
An Analysis of the So-called Normal Mortality in Poultry Flocks
, 1922 Willard C. Thompson
openalex +1 more source