Stability of the Brascamp-Lieb constant and applications [PDF]
We prove that the best constant in the general Brascamp-Lieb inequality is a locally bounded function of the underlying linear transformations. As applications we deduce certain very general Fourier restriction, Kakeya-type, and nonlinear variants of the
Bennett, Jonathan +3 more
core +3 more sources
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Differences in receptivity to gastrointestinal infections with nematodes in dairy ewes: Influence of age and of the level of milk production [PDF]
Resistance to anthelmintics in populations of gastrointestinal nematodes is a major concern in small ruminants. One solution to limit the spread of anthelmintic resistance is to apply treatments selectively by targeting the most susceptible animals ...
A.C., Rulie +7 more
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Hydrodynamics of Turning Flocks
We present a hydrodynamic model of flocking that generalizes the familiar Toner-Tu equations to incorporate turning inertia of well-polarized flocks.
Marchetti, M. Cristina, Yang, Xingbo
core +1 more source
Robust Q‐learning‐based multi‐objective sheep flock optimizer with a Cauchy operator for effective path planning in unmanned aerial vehicles [PDF]
Vikash Kumar, Seemanti Saha
openalex +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The control of parasitic nematode infection in sheep and other animals is threatened by the evolution of drug resistance in parasite populations. One recommendation to delay the onset of drug resistance is to estimate the flock mean faecal egg counts by ...
Michael Stear +4 more
doaj +1 more source
An effective rotational mating scheme for inbreeding reduction in captive populations illustrated by the rare sheep breed [PDF]
Within breeds and other captive populations, the risk of high inbreeding rates and loss of diversity can be high within (small) herds or subpopulations.
Lansbergen, L.M.T.E., Windig, J.J.
core +3 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source

