Results 131 to 140 of about 202,210 (324)

Flocking at the edge of chaos

open access: yes, 2015
Recent investigations have provided important insights into the complex structure and dynamics of collectively moving flocks of living organisms. Two intriguing observations are, scale-free correlations in the velocity fluctuations, in the presence of a ...
Bhattacharya, Kunal   +1 more
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Organic Farming in Cornwall: Results of the 2002 Farmer Survey [PDF]

open access: yes, 2003
A detailed survey of organic farming in Cornwall was completed duing the period August 2002 to February 2003. One of the main objectives of the survey was to describe current practices and constraints to organic production so as to aid the Organic ...
Burke, Jean, Roderick, Stephen
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

On Non-hyperelliptic Flocks

open access: yesEuropean Journal of Combinatorics, 1994
Let \(K\) be the quadratic cone of \(PG (3,q)\) with vertex \(v = (0,0,0,1)\) and equation \(X_0 X_1 = X_2^2\). A flock \(F\) of \(K\) is a partition of \(K \backslash \{v\}\) into \(q\) disjoint irreducible conics. Associated to each flock \(F\) is a translation plane \(T(F)\) of order \(q^2\) and dimension at most two over its kernel.
BADER, LAURA, LUNARDON, GUGLIELMO
openaire   +2 more sources

Chalk streams and grazing mute swans [PDF]

open access: yes, 2014
The evidence shows that swan grazing can reduce plant abundance, prevent flowering, reduce water depth and reduce fishery value. However, these effects seem to be limited to a small number of sites on larger chalk streams.
Daunt, Francis   +3 more
core  

Potential risk factors associated with contact dermatitis, lameness, negative emotional state, and fear of humans in broiler chicken flocks.

open access: yesPoultry Science, 2013
The objectives of this study were to 1) identify determinants of poor welfare in commercial broiler chicken flocks by studying the associations between selected resource-based measures (RBM, potential risk factors), such as litter quality and dark period,
A. Bassler   +9 more
semanticscholar   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

The toxic sheep collar for control of sheep-killing coyotes: A progress report [PDF]

open access: yes, 1978
The toxic sheep collar is the most selective method known for killing coyotes that prey on domestic sheep. The concept dates back to the early 1900's and has been studied at the Denver Wildlife Research Center (DWRC) since 1974.
Connolly, Guy E.   +2 more
core  

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