Results 231 to 240 of about 202,210 (324)

A report of the in-farm variation of antimicrobial use in commercial broiler production in Pakistan using an international monitoring system based on treatment frequency. [PDF]

Front Vet Sci
Rehberg B, Brogden S, Fatima F, Umair M, Hartmann M, Kschonek J, Farooq U, Mohsin M, Kreienbrock L.   +8 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Molecular and Serological Detection of Coxiella burnetii in Small Ruminants in Northeastern Brazil. [PDF]

Vet Med Sci
Simas AKSM, Mioni MSR, Costa APD, Teixeira WSR, Cardoso ADS, Nogueira RMS, Megid J, Costa FB.   +7 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Controlling noisy herds: Temporal network restructuring improves control of indecisive collectives. [PDF]

Sci Adv
Chakrabortty T, Bhamla S.
europepmc   +1 more source

Enumeration of Salmonella and Campylobacter spp. in Environmental Farm Samples and Processing Plant Carcass Rinses from Commercial Broiler Chicken Flocks

Applied and Environmental Microbiology, 2013
R. Berghaus, S. Thayer, B. Law, R. Mild, C. Hofacre, R. Singer   +5 more
semanticscholar   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Evaluation of Pulsed Alternating Wavelength System Lighting on the Welfare Quality and Serotonin Turnover of Commercial Laying Hens Throughout a Lay Cycle. [PDF]

Animals (Basel)
Emmert BJ, Tonissen S, Schober JM, Fraley GS, Karcher DM.   +4 more
europepmc   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

Extending laying hens' productive lifespan by molting: a pilot on-farm study and test of assessment methods with focus on functional traits and keel bone health. [PDF]

Poult Sci
Gickel J, Broszat F, Salzmann L, Kemper N, Jung L.   +4 more
europepmc   +1 more source