Results 41 to 50 of about 211 (146)
Histamine H4 receptor (H4R) antagonist VUF6002 mimics low‐dose X‐ray irradiation in aged Alzheimer's disease (AD) mice, enhancing microglial clearance of amyloid‐beta/hyperphosphorylated tau aggregates and restoring cognition. Microglial H4R deletion activates cAMP/TGF‐β1/Smad3 pathway, enhancing phagocytosis, while TGF‐β receptor 1 deletion abolishes ...
Yi‐Jun Xu +5 more
wiley +1 more source
Cortically Dependent Motor Training Does Not Induce Abnormal Movements in DYT1‐Knock In Mice
DYT1 dystonia is a familial autosomal dominant, childhood onset dystonia. Mouse models recapitulating the human genotype do not exhibit overtly dystonic movements. It is unclear whether cortically‐dependent tasks are necessary for the development of dystonic movements.
Alexander T. Hodge +4 more
wiley +1 more source
Given three angles summing to 2, given n points in the plane and a tripartition k1 + k2 + k3 = n, we can tripartition the plane into three wedges of the given angles so that the i-th wedge contains ki of the points. This new result on dissecting point sets is used to prove that lights of specied angles not exceeding can be placed at n xed points in the
Bose, F. +5 more
openaire +3 more sources
Illumination of polygons by 45°-floodlights
AbstractWhat is the minimal number of floodlights that can illuminate the interior of any polygon with n vertices, provided that every floodlight has an α,α∈(0°,360°], range of illumination? This question is answered in this paper for α∈[45°,60°), stating that this number is n−1, if n is odd, and n−2, if n is even.
openaire +1 more source
Beyond Moral Outrage: The Role of the Ingroup in Online Condemnations
ABSTRACT Although expressions of condemnation are pervasive on social media and often shape the narratives of traditional news outlets, brands continue to struggle with predicting and managing these responses effectively. To address this challenge, it is crucial to first understand the underlying reasons for such behavior.
Jeff D. Rotman +3 more
wiley +1 more source
Floodlighting luminaire for homogeneous illumination
The main subject of the research is a proposition of a luminaire optical system which allows us to illuminate building facades in a more uniform way than it is today in the case when luminaire location is close and asymmetric to the illuminated object ...
Kubiak, K.
core
When Social Sharing Increases Pride in Customized Products
ABSTRACT In the marketplace, customers often customize products. Enabled by technological advances, companies can encourage customers to share these customization experiences (e.g., via social sharing buttons) with others, such as friends. Across six studies with mixed methods (field, lab, online) and in various product domains (food, fitness trackers,
Rocío Alarcón‐López +2 more
wiley +1 more source
Essential Validation Criteria for Rigorous Covariance‐Based Structural Equation Modelling
ABSTRACT Covariance‐based structural equation modelling (CB‐SEM) is a robust analytical technique for validating complex measurements and theoretical models. Despite criticisms regarding overfitting, misspecification and sample size limitations, SEM remains invaluable for rigorous theoretical model testing when applied correctly.
James E. Gaskin +3 more
wiley +1 more source
Abstract For firms facing an aging society, substantial adoption gaps that often exist for new product alternatives between older and younger consumers pose a significant challenge. To examine the root cause of this phenomenon, our research draws on life‐span theory and is based empirically on a set of studies involving 2050 participants in both field ...
Dominik Hettich +2 more
wiley +1 more source

