Results 41 to 50 of about 404,117 (334)

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Sublingual Dermoid Cyst in Young Child

Children, 2023
A dermoid cyst is a benign congenital lesion of ectodermal origin that can arise in any region of the body, though occurrence is rare. A young girl aged 2 years 4 months was referred to our hospital because of a painless mass in the floor of the mouth ...
Masakazu Hamada, Rena Okawa, Katsuhiko Masuda, Fumikazu Tojo, Yuto Suehiro, Yuko Ogaya, Hiroko Kinosada, Narikazu Uzawa, Kazuhiko Nakano   +8 more
doaj   +1 more source

Oral ranula : report of a case with review of literature [PDF]

, 2018
Ranula is a soft bluish translucent swelling that occurs in floor of mouth usually causing mild discomfort to the patient. Ranula can be categorized as simple or plunging.
Abdelatty Eid Abdemagyd, Hossam, Ram Shetty, Shishir, Said Hamed, Mohammed   +2 more
core  

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Profiling the effect of low frequency mechanical vibration on the metabolic and oxidative stress responses of A431 carcinoma

FEBS Open Bio, EarlyView.
20 Hz mechanical vibration induced A431 cancer cells' apoptosis without such effect on other healthy cell lines of L929 and C2C12. Lowered glucose consumption is observed specifically in A431. The expressions of ROS, HMGB1, and HSP1 levels initially increase and subsequently decrease in the cancer cell line, as opposed to L929 and C2C12, which ...
Wresti L. Anggayasti, Chikahiro Imashiro, Takashi Morikura, Shogo Miyata, Akira Funahashi, Kenjiro Takemura   +5 more
wiley   +1 more source

Alveolar Rhabdomyosarcoma of Oral Cavity – A Rare Case [PDF]

Al Ameen Journal of Medical Sciences, 2010
Rhabdomyosarcomas are the malignant tumors of the striated skeletal muscles. Rhabdomyosarcomas are the most common soft tissue sarcoma of the children, adolescents and young adults. An eleven year old boy who presented with a painless progressive lump in
Ravi Batra, D.O.Gupta, Pooja Sharma, Pradeep Bokariya   +3 more
doaj  

Multiple synchronous rhabdomyomas in the tongue and floor of the mouth: case report

Journal of Oral Medicine and Oral Surgery, 2019
Observation: A 61-year-old male patient presented with tongue and base floor of the mouth firm swelling with intact overlying mucosa with ballottement by bimanual palpation.
Sweed Ahmed Hassan, Bolzoni Alessandro, Anna Beltramini Giada, Baj Alessandro   +3 more
doaj   +1 more source

Validity and Reliability of Clinical and Patient‐Reported Outcomes in Multisystem Proteinopathy 1

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Valosin‐containing protein (VCP)‐associated multisystem proteinopathy 1 (MSP1) is caused by variants in the VCP gene. MSP1 results in various phenotypes including progressive myopathy, Paget's disease of bone, frontotemporal dementia, amyotrophic lateral sclerosis, and parkinsonism, among others.
Lindsay N. Alfano, Megan A. Iammarino, Natalie F. Reash, Linda P. Lowes, Lindsay Pietruszewski, Kathleen Adderley, Lauren Humphrey, Audrey B. Knight, Christopher L. Steiner, Melissa A. Smith, Zarife Sahenk, Anne M. Connolly, Momen Almomen, Eleonora S. D'Ambrosio, Nathan Peck, Allison Peck   +15 more
wiley   +1 more source

The difficult diagnosis of floor of the mouth masses: a case report

The Egyptian Journal of Otolaryngology
Background Lymphatic malformations can present as a floor of the mouth mass, they are rare vascular lesions, presenting most frequently in the head and neck region and mostly presenting at birth or before 2 years of age.
Alexe De Ferm, Bart Van Boven, Maaike Cornelis, Rafael Jacobs   +3 more
doaj   +1 more source