Activation of NF‐κB Signaling by Optogenetic Clustering of IKKα and β
This study presents an optogenetic approach for graded clustering of eGFP‐fused proteins using an eGFP‐specific nanobody and engineered Cryptochrome 2 variants. The method enables potent, reversible activation of NF‐κB signaling via endogenous pathways, as confirmed by RNA sequencing. This versatile system provides a spatially and temporally controlled
Alexandra Anna Maria Fischer+8 more
wiley +1 more source
Tipificación y estatus raxonómico de Centaurea resupinata subsp. virens (sect. Willkommia Blanca, Asteraceae) [Typification and taxonomic status of Centaurea resupinata subsp. virens comb. et stat. nov. (Sect. Willkommia Blanca, Asteraceae)] [PDF]
RESUMEN: Se reivindica el valor taxonómico y lectotipifica el nombre de Centaurea incana Lag. (non auct.) β virens (Sect. Willkommia Blanca, Asteraceae) propuesto por Carlos Pau para describir una planta presente en la sierra litoral valenciana de ...
P. Pablo FERRER GALLEGO+6 more
doaj
Using supramolecular monomers, various hydrogel culture systems were formulated to culture protoplasts; including 2D, 2.5D, and 3D hydrogels. Depending on the culture platform, bioactive functionalization led to protoplast enlargement (2D and 2.5D) or plasmolysis (3D). This work shows the potential to modularly engineer synthetic platforms for cellular
Maritza M. Rovers+3 more
wiley +1 more source
Dos nuevos narcisos híbridos en el occidente de la península ibérica [Two new Narcissus in Western Iberian Peninsula] [PDF]
Se describen las nuevas especies híbridas Narcissus ×villasrubiensis González, Patino, Solís & Urrutia [N. triandrus L. subsp. pallidulus (Graells)] Rivas Goday × N. vitekii P.
Antonio GONZÁLEZ+3 more
doaj
The invasive pest Halyomorpha halys causes significant crop losses requiring innovative pest control strategies such as RNA interference (RNAi). However, oral RNAi is largely ineffective in H. halys. This study shows that double‐stranded DNA (dsDNA) stabilizes dsRNA in saliva by inhibiting a highly expressed nuclease.
Venkata Partha Sarathi Amineni+2 more
wiley +1 more source
Media docena de cartas de Romualdo González Fragoso a Francisco Beltrán Bigorra (1913-14) [Six letters of Romualdo Gonzalez Fragoso to Francisco Beltrán Bigorra (1913-14)] [PDF]
RESUMEN: Estudio de seis cartas de Romualdo González Fragoso a Francisco Beltrán Bigorra, con noticias de los estudios biológicos que ambos realizaban los años 1913 y 1914, así como sobre las peculiares relaciones científicas que mantenían con otros ...
José María de Jaime Ruiz+3 more
doaj
Flora of Middle-earth (2017) by Walter S. Judd and Graham A. Judd [PDF]
Book review by Martin Simonson of Flora of Middle-earth (2017) by Walter S.
Simonson, Martin
core +2 more sources
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang+6 more
wiley +1 more source
Correspondencia epistolar de Carlos Vicioso a Carlos Pau durante su estancia en Bicorp (Valencia) [Epistolary correspondece between Carlos Vicioso and Carlos Pau during a stay in Bicorp (Valencia)] [PDF]
RESUMEN: Se presenta y comenta un conjunto de cartas enviadas por Carlos Vicioso a Carlos Pau durante su estancia en Bicorp (Valencia) entre 1914 y 1915.
Pedro Pablo Ferrer Gallego
doaj