Results 31 to 40 of about 511,411 (299)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Herpetofaunal diversity and sampling efficacy in the Upper Guinean rainforest

Acta Herpetologica
The upper Guinean rainforest biome is a poorly studied, yet hyper-biodiverse region facing severe fragmentation due to ongoing habitat transformation. We conducted a herpetological baseline survey in the Dugbe region during 2021 using passive trapping ...
Ryan van Huyssteen, Melissa Petford, Marius Burger, Trokon Superior Grimes, Jerome Gaugris   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Estratègia catalana de conservació ex situ de la flora vascular silvestre [PDF]

, 2011
Flora amenazada—Cataluña; Flora vascular silvestreLa conservació de flora ex situ consisteix a mantenir fora del seu hàbitat natural qualsevol part d’una planta a partir de la qual es pugui restituir altre cop una població en estat salvatge. Les parts de
Canalias, Francesc, Pujol, Xavier, Membrives, Núria, Sala, Esther, Gifre, Cristina, Colom, Albert, Rosselló, Josep Antoni   +6 more
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Dialuoghi, una porta per la Sanità. Diarc: dalla ricerca accademica al progetto per realizzare un nuovo futuro [PDF]

, 2021
Il volume, partendo da esperienze condotte di ricerca applicata nel Dipartimento di architettura della Federico II di Napoli, ragiona intorno all'occasione determinatasi a partire da istanze della comunità del Rione Sanità, di aumentare i punti di ...
Nicola Flora, Flora, Nicola
core  

Diversity of anurans and use of microhabitats in three vegetation coverages of the Santuario de Flora y Fauna Los Colorados, Colombian Caribbean

Revista Mexicana de Biodiversidad
This study aimed to determine anuran diversity and the use of microhabitats in 3 vegetation covers in the Santuario de Flora y Fauna Los Colorados. Five field trips of 6 days each were made, 2 days and 2 nights in each cover: forest, pasture, and crop ...
Omer José Jiménez-Ortega, Keiner L. Tílvez, Joselin Castro-Palacios, Andrés García, Gabriel R. Navas, Julio Abad Ferrer-Sotelo, Dilia Naranjo-Calderón, Juan Gabriel Díaz-Castellar, Víctor Buelvas-Meléndez   +8 more
doaj   +1 more source