Microtopography enhances intestinal drug absorption via Piezo1‐mediated tight junction modulation
Microtopography‐driven enhancement of oral peptide drug delivery by activating Piezo1 channels significantly improves paracellular permeability and bioavailability, offering a novel approach for optimizing macromolecule absorption in pharmaceutical formulations.
Yu Hu +12 more
wiley +1 more source
Plant-pollinator interactions and floral and nectar traits shape the diversity of the nectar mycobiome. [PDF]
Kisło K +7 more
europepmc +1 more source
This study reports the development of AMS@Eud core‐shell microspheres, combining calcium alginate and pH‐responsive Eudragit® L100, which exhibit exceptional gastrointestinal resistance and long‐term storage stability (only 5.28%–9.09% viability loss over 35 days at 4–25°C), and effectively alleviate inflammatory bowel disease via gut microbiota ...
Ming Teng +5 more
wiley +1 more source
TPS-mediated transcription reprogramming during the robust aroma formation in Daphne odora flowers. [PDF]
Zhao K +11 more
europepmc +1 more source
Enhanced strategies for cuproptosis‐like death in bacterial infection treatment
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang +7 more
wiley +1 more source
Chromosome-level genome of <i>Madhuca hainanensis</i> reveals genomic evolution and floral divergence in <i>Madhuca</i>. [PDF]
Ma Y +6 more
europepmc +1 more source
Adaptive Genomic Divergence Across Altitudes in Capsella bursa‐pastoris
Genomic divergence was observed between high‐altitude and low‐altitude populations of Capsella bursa‐pastoris in China, consistent with an important role of ecological factors. Candidate adaptive loci associated with enhanced energy metabolism, photoprotection, and growth plasticity under altitudinal stress were identified.
Lu Liu +4 more
wiley +1 more source
Identification of the PoARFs gene family in tree peony and expression analysis of PoARF7 and PoARF10 in petals and stamens formation. [PDF]
Zhou Y +8 more
europepmc +1 more source
We ought to discuss the social construction of cadavers: Here's why and how
Anatomical Sciences Education, EarlyView.
Fatima Ehsan, Susan Lamb
wiley +1 more source
Spatial metrics in fire ecology: seeking consistency amidst complexity
ABSTRACT Technological advances, including remote sensing, have led to a proliferation of metrics used in ecological studies to examine spatial patterns of fire regimes and their ecological effects. Researchers can use many different metrics to analyse spatial variation in both fire events and resulting fire regimes, including fire size, shape ...
Alexander R. Carey +5 more
wiley +1 more source

