Results 31 to 40 of about 861,639 (295)

Urban sustainability in Old City Centres, a Comparison Between the City of Najaf in Iraq and Italian Cities Experiences [PDF]

open access: yesEngineering and Technology Journal, 2016
This paper discusses the current situationinold cities ofIraq, whichis not commensuratewiththe highprestige andsanctity ofwhatit containsandwhatit represents of rarityandtypicality.
Sabeeh Lafta Farhan   +2 more
doaj   +1 more source

Nuclear lattice simulations: Status and perspectives

open access: yes, 2013
I review the present status of nuclear lattice simulations. This talk is dedicated to the memory of Gerald E. Brown.Comment: Plenary talk sponsored by The European Physical Journal A -- Hadrons and Nuclei, INPC 2013, Florence, Italy, 8 pages, 3 ...
Meißner, Ulf-G.
core   +2 more sources

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

1st Report of the Working Group on Standard Development [PDF]

open access: yes, 2003
The initial meeting of the working group on standard development took place at the 1st SAFO-Workshop, September 2003, in Florence. In accordance with the main topic of the Workshop, the discussion was primarily focused on the relationship between socio ...
Sundrum, Albert, Walkenhorst, Michael
core  

Antibody-mediated cross-linking of gut bacteria hinders the spread of antibiotic resistance [PDF]

open access: yes, 2019
The body is home to a diverse microbiota, mainly in the gut. Resistant bacteria are selected for by antibiotic treatments, and once resistance becomes widespread in a population of hosts, antibiotics become useless. Here, we develop a multiscale model of
Bansept, Florence   +3 more
core   +2 more sources

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone   +8 more
wiley   +1 more source

Мастерская Эмбриаки как исторический конструкт

open access: yesИскусство Евразии
На протяжении многих десятилетий большая часть итальянской костяной продукции XIV–XV веков приписывалась мастерской Эмбриаки. Неразрывная связь предметов и имени фактически стала удобным и привычным шаблоном для музейных каталогов и аукционных продаж ...
Савченкова, А.А.
doaj   +1 more source

Leonardo Ricci and Leonardo Savioli. An Epistolary Novel. 1943-1944

open access: yesHistories of Postwar Architecture, 2023
Through unpublished letters written by Leonardo Ricci to his friend Leonardo Savioli in 1943 and 1944, the paper aims to trace the early period of the two architects' careers.
Lorenzo Mingardi
doaj   +1 more source

MYCOPHENOLATE MOFETIL TREATMENT REDUCES THE RISK OF TREATMENT ESCALATION DUE TO VASCULAR COMPLICATIONS IN LIMITED CUTANEOUS SYSTEMIC SCLEROSIS: EMULATION OF A TARGET TRIAL FROM ITALIAN RHEUMATOLOGY SOCIETY SPRING REGISTRY

open access: yesArthritis Care &Research, Accepted Article.
Objective Mycophenolate Mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon due to the lower fibrotic burden and the predominance of the vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis   +77 more
wiley   +1 more source

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