Results 31 to 40 of about 105,686 (259)

Urban sustainability in Old City Centres, a Comparison Between the City of Najaf in Iraq and Italian Cities Experiences [PDF]

open access: yesEngineering and Technology Journal, 2016
This paper discusses the current situationinold cities ofIraq, whichis not commensuratewiththe highprestige andsanctity ofwhatit containsandwhatit represents of rarityandtypicality.
Sabeeh Lafta Farhan   +2 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone   +8 more
wiley   +1 more source

Мастерская Эмбриаки как исторический конструкт

open access: yesИскусство Евразии
На протяжении многих десятилетий большая часть итальянской костяной продукции XIV–XV веков приписывалась мастерской Эмбриаки. Неразрывная связь предметов и имени фактически стала удобным и привычным шаблоном для музейных каталогов и аукционных продаж ...
Савченкова, А.А.
doaj   +1 more source

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto   +12 more
wiley   +1 more source

Leonardo Ricci and Leonardo Savioli. An Epistolary Novel. 1943-1944

open access: yesHistories of Postwar Architecture, 2023
Through unpublished letters written by Leonardo Ricci to his friend Leonardo Savioli in 1943 and 1944, the paper aims to trace the early period of the two architects' careers.
Lorenzo Mingardi
doaj   +1 more source

Interaction of Intraprocedural Antiplatelets and Intravenous Thrombolysis in Acute Intracranial Stenting: RESISTANT Registry Subanalysis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes   +75 more
wiley   +1 more source

Initial experiences of an english-speaking digital assistant for tobacco cessation in India

open access: yesIndustrial Psychiatry Journal
Background: The WHO tobacco control team established the Access Initiative for Quitting Tobacco (AIQT) in July 2020. The AIQT team developed a virtual assistant “Florence” to provide digital counseling services to people willing to quit tobacco.
Enub Ali   +3 more
doaj   +1 more source

«THE SERVANT OF GOD WISHED TO TURN THE DISSOLUTE DAY INTO THE DAY OF PRUDENCE, HOLINESS AND GOOD FOR THE SOUL»

open access: yesВестник Северо-Кавказского федерального университета, 2022
This article deals with practice on organization of «bonfire of vanities» in Florence in the late 15th century, at the same time special attention is paid to connection between Savonarola «pious» holidays аnd carnival culture.
Elena P. Telmenko
doaj  

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