Results 181 to 190 of about 13,748 (211)

Pharmacokinetics of florfenicol and florfenicol‐amine after intravenous administration in sheep

Journal of Veterinary Pharmacology and Therapeutics, 2011
Florfenicol (FFC) is a broad spectrum antibacterial agent that is structurally related to chloramphenicol but differs from it by the presence of a para-methyl sulphonyl group instead of the p-nitro group and the presence of a fluorine atom instead of the hydroxyl group in the terminal primary alcohol function (EMEA, 2002).
C, Palma, J, Ramírez, A, Benavente, V, Cazanga, M, Venegas, R, Pérez   +5 more
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Pharmacokinetics of florfenicol and its major metabolite, florfenicol amine, in rabbits

Journal of Veterinary Pharmacology and Therapeutics, 2007
The pharmacokinetics of florfenicol and its active metabolite florfenicol amine were investigated in rabbits after a single intravenous (i.v.) and oral (p.o.) administration of florfenicol at 20 mg/kg bodyweight. The plasma concentrations of florfenicol and florfenicol amine were determined simultaneously by an LC/MS method. After i.v.
B-K, Park, J-H, Lim, M-S, Kim, Y-H, Hwang, H-I, Yun   +4 more
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Pharmacokinetics of Florfenicol and Its Metabolite Florfenicol Amine in Atlantic Salmon

Journal of Aquatic Animal Health, 1996
Abstract The plasma pharmacokinetic profile of the antibacterial agent florfenicol was studied in Atlantic salmon Salmo salar in seawater. In a single-dose study, each fish was given 10 mg/kg body weight by intravenous (iv) injection or by oral gavage of feed coated with the drug.
Tor Einar Horsberg, Kjell Arne Hoff, Rolf Nordmo   +2 more
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Approaches for the simultaneous detection of thiamphenicol, florfenicol and florfenicol amine using immunochemical techniques

Journal of Immunological Methods, 2013
Thiamphenicol and florfenicol are antibacterial agents permitted for use as veterinary drugs in animals used for food production. However, as the EU has established maximum residue limits for both and the metabolite florfenicol amine, there is a requirement to monitor animal food products for their residues.
Fodey, Terence L., George, Suja E., Traynor, Imelda M., Delahaut, Philippe, Glenn Kennedy, D., Elliott, Christopher T., Crooks, Steven R.H.   +6 more
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Pharmacokinetics and tissue distribution of florfenicol and florfenicol amine in snubnose pompano (Trachinotus blochii) following oral administration

Fish Physiology and Biochemistry, 2023
The present study reports the comparative pharmacokinetic profiles of florfenicol and its metabolite (florfenicol amine, FFA) in Trachinotus blochii under tropical marine conditions (salinity: 35 ± 1.4‰; temperature: 28.8 ± 0.54 °C) following a single in-feed oral administration of the recommended dose (15 mg/Kg).
T. G. Sumithra, S. R. Krupesha Sharma, Vishnu Prasad, Ambarish P. Gop, Suja Gangadharan, S. Gayathri, Antony Ambrose, R. Rajisha, S. K. Panda, M. K. Anil, P. K. Patil   +10 more
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UPLC–MS/MS determination of florfenicol and florfenicol amine antimicrobial residues in tilapia muscle

Journal of Chromatography B, 2016
Despite the benefits to fish farmers, the use of antimicrobials in aquaculture has concerned consumers and competent authorities. The indiscriminate use of such substances promotes the emergence of resistant microorganisms, decreases the effectiveness of treatments, and causes possible toxic effects in humans.
Eduardo Adilson, Orlando, Aline Gabriela, Costa Roque, Marcos Eliseu, Losekann, Ana Valéria, Colnaghi Simionato   +3 more
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Determination of extractable and non-extractable florfenicol residues as florfenicol amine in eggs by UPLC-MS/MS

Food Additives & Contaminants: Part A, 2022
Some florfenicol (FF) metabolites have a strong binding affinity towards biomolecules in the edible tissues of some food animals. These bound FF residues cannot be extracted directly from edible tissues with organic solvents and are present in higher concentrations even than solvent extractable residues.
Xia, Li, Yu, Zhang, Qifan, Sun, Min, Ding, Zengmei, Li, Hui, Yue, Ligang, Deng, Lu, Chen   +7 more
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Pharmacokinetics of florfenicol in veal calves

Journal of Veterinary Pharmacology and Therapeutics, 1986
Varma, K.J., Adams, P.E., Powers, T.E., Powers, J.D. & Lamendola, J.F. Pharmacokinetics of florfenicol in veal calves. J. vet. Pharmacol. Therap. 9, 412–425.The pharmacokinetic disposition of florfenicol was described in veal calves after administration of a single 22‐mg/kg dose intravenously, orally after a 12‐h fast and orally 5 min post feeding.
K J, Varma, P E, Adams, T E, Powers, J D, Powers, J F, Lamendola   +4 more
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Residue Depletion of Florfenicol and Its Metabolite Florfenicol Amine in Swine Tissues after Intramuscular Administration

Journal of Agricultural and Food Chemistry, 2006
A study of the tissue depletion of florfenicol (FF) administered intramuscularly twice to swine at a dose rate of 20 mg per kg of body weight at 24 h intervals was carried out. Forty healthy cross swine were treated with the FF injection formulation.
Jiancheng, Li, Shuangyang, Ding, Suxia, Zhang, Cun, Li, Xiaowei, Li, Zhongwei, Liu, Jinfeng, Liu, Jianzhong, Shen   +7 more
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Pharmacokinetics of florfenicol and its metabolite, florfenicol amine, in the Korean catfish (Silurus asotus)

Journal of Veterinary Pharmacology and Therapeutics, 2006
The pharmacokinetics of florfenicol and its metabolite, florfenicol amine, was investigated after its intravenous (i.v.) and oral (p.o.) administration of 20 mg/kg of body weight in Korean catfish (Silurus asotus). After i.v. florfenicol injection (as a bolus), the terminal half‐life (t1/2), the volume of distribution at steady state (Vdss), and total ...
B-K, Park, J-H, Lim, M-S, Kim, H-I, Yun
openaire   +2 more sources