Results 31 to 40 of about 4,963 (229)

A Brain‐Wide Atlas of Astrocytic Oxytocin Receptors Reveals a Glial Basis for Nucleus Accumbens Modulation of Affiliative Behavior

Advanced Science, EarlyView.
The cellular actors of oxytocin signaling are under intense scrutiny. A brain‐wide anatomical and functional analysis in mice and rats reveals widespread expression of oxytocin receptors in astrocytes. These receptors are functionally active and, in the nucleus accumbens, selectively regulate male social affiliation.
Clémence Denis, Stefan Stojilkovic, Kai‐Yi Wang, Cristina Márquez, Annabel C. Kleinwächter, Angel Baudon, Yuval Podpecan, Aurélia Ces, Mélanie Kremer, Isabelle Arnoux, Nathalie Rouach, Jemima Helen, Sophie Trender, Andreas Wallkum, Selina Wunsch, Franziska Schommer, Moritz C. Wimmer, Tim Schubert, Felix Franke, Jabir Aliyu Muhammad, Eva M. Eisemann, Ingrid Camila Possa‐Paranhos, Cassandra Baumann, Pierre‐Alexis Derrien, Quirin Krabichler, Cosmo Garcia, Henning Fröhlich, Matthew K. Kirchner, Valery Grinevich, Pascal Darbon, Javier E. Stern, Ferdinand Althammer, Alexandre Charlet   +32 more
wiley   +1 more source

CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation

Advanced Science, EarlyView.
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu, Cheng Kiu Ho, Jitao Liu, Lei Cui, Yangfeng Hou, Cai Liang, Wenchu Ye, Randolph H. L. Wong, Shohei Hori, Bin Zhou, Kathy O. Lui   +10 more
wiley   +1 more source

Longan Growing in the Florida Home Landscape

EDIS, 2013
This document provides a comprehensive overview of the longan tree, including its botanical description, cultivation practices, and environmental stress physiology. It details the tree's origin, distribution, and economic importance, particularly in Florida.
J.H. Crane, C.F. Balerdi, S.A. Sargent, Ian Maguire   +3 more
openaire   +1 more source

eQTL Meta‐Analysis Reveals Conserved and Population‐Specific Regulatory Variation Underlying Nutritional Trait Evolution and Domestication in Tomato

Advanced Science, EarlyView.
A comprehensive meta‐analysis of expression quantitative trait loci (eQTLs) across five diverse tomato populations reveals a high‐resolution atlas of transcriptional regulation and uncovers conserved and population‐specific regulatory architectures underlying fruit nutritional quality traits, including flavonoids, sugars, organic acids, carotenoids ...
Jiantao Zhao, Xin Wang, Jing Zhang, Ryan McQuinn, Je Min Lee, Itay Gonda, Ari Feder, Yimin Xu, Baike Wang, Qinghui Yu, Denise M. Tieman, Sanwen Huang, Harry Klee, James J. Giovannoni, Zhangjun Fei   +14 more
wiley   +1 more source

Chemoproteomic Identification of AKT2 as a Paclitaxel‐Binding Protein via C─C Bond‐Linked Probe PTX‐4 in Paclitaxel‐Resistant Breast Cancer

Advanced Science, EarlyView.
ABSTRACT Breast cancer remains one of the most prevalent malignancies among women, and taxane‐based chemotherapies such as paclitaxel and docetaxel are central to standard treatment regimens. However, drug resistance in breast cancer limits therapeutic efficacy and contributes to recurrence and metastasis.
Kai Wang, Yuqing Yuan, Wei Shen, Xiuxiu Yang, Xiaokang Wu, Haihua Zhou, Yi Hu, Qing Zhu   +7 more
wiley   +1 more source

Climate change in reclamation landscapes – Adaptation between module and modularity

Agathón, 2023
Modern drainage of wetlands has produced landscapes that are expressions of a productive view of natural space. These landscapes result from a profound environmental transformation driven by economic, social, health, and cultural reasons.
Carla Brisotto, Jeff Carney, Ina Macaione, Alessandro Raffa   +3 more
doaj   +1 more source

Adopting a Florida-Friendly Landscape: Steps for Converting a Typical Development Landscape to a Florida-Friendly Landscape

EDIS, 2009
ENH-1135, a 15-page illustrated fact sheet by Gail Hansen, Jennifer Ramos, E.A. Felter, and Celeste White, lays out a process of incorporating more trees and plants in three phases, to make a traditional development landscape more environmentally sound and Florida-Friendly. Includes references.
Gail Hansen de Chapman, Jennifer Ramos, Elizabeth A. Felter, Celeste White   +3 more
openaire   +3 more sources

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

Home Irrigation and Landscape Combinations for Water Conservation in Florida

EDIS, 2005
Irrigation has become commonplace for residential homeowners desiring high quality landscapes in Florida. Turfgrass is a key landscape component and normally the most commonly used single type of plant in the residential landscape.
Melissa B. Haley, Michael D. Dukes, Grady L. Miller, Dorota Z. Haman   +3 more
doaj   +3 more sources

Sapodilla Growing in the Florida Home Landscape

EDIS, 2006
Revised! HS-1, a 10-page fact sheet by Carlos F. Balerdi, Jonathan H. Crane, and Ian Maguire, provides homeowners with a basic reference for growing sapodilla in the home landscape. Tables include information on selected cultivars for Florida, cultural practices by month, fertilizer program, and nutritional information.
Carlos F. Balerdi, Jonathan H. Crane, Ian Maguire   +2 more
openaire   +2 more sources