Results 241 to 250 of about 6,303 (299)

Homeobox B13 activates the hypoxia‐inducible factor 1 pathway through histone lactylation thereby reprogramming lipid metabolism and promoting sorafenib resistance in hepatocellular carcinoma

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Lactylation‐mediated metabolism reprogramming in HCC sorafenib resistance. In sorafenib‐resistant hepatocellular carcinoma (HCC) cells, lactate accumulation drives histone H3 lysine 18 lactylation (H3K18la). This modification is specifically enriched in the promoter region of homeobox B13 (HOXB13), activating HOXB13 transcription and upregulating its ...
Qingqing Xie   +5 more
wiley   +1 more source

Measuring Calcium Efflux in Isolated Primary Mitochondria

open access: yesCurrent Protocols, Volume 6, Issue 6, June 2026.
Abstract Mitochondrial calcium (mCa2+) homeostasis promotes oxidative metabolism within the physiological range; however, dysregulation can trigger necrotic cell death in diseases such as cardiac ischemia‐reperfusion injury, muscular dystrophy, and neurodegenerative disorders, including Alzheimer's disease.
Ta'Aliyah M. Jones   +2 more
wiley   +1 more source

Occurrence of Microplastics and Cytotoxic Effects of Organic Extracts from Isolated Mesoplastics in Compost. [PDF]

open access: yesACS Omega
Sánchez-Argüello P   +5 more
europepmc   +1 more source

Recent Progress of Mineral Flotation Reagents

open access: yesJournal of the Mining Institute of Japan, 1961
openaire   +2 more sources

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