Results 91 to 100 of about 278,570 (272)

Conversion of Transplanted Mature Hepatocytes into Afp+ Reprogrammed Cells for Liver Regeneration After Injury

Advanced Science, EarlyView.
Donor‐derived tdTomato+ mature hepatocytes were FACS‐isolated and transplanted into Fah−/− host mice. During regeneration, these cells convert into proliferative, unipotent Afp+ rHeps. Their plasticity is governed by a PPARγ/AFP‐dependent metabolic switch, segregating into pro‐proliferative Afplow and pro‐survival Afphigh subpopulations.
Ting Fang, Chao Yang, Hua Qiu, Yuan Du, Xicheng Wang, Yuting Li, Mingyang Xu, Changcheng Liu, Xiuhua Li, Na Guo, Jun Shi, Wencheng Zhang, Zhiying He   +12 more
wiley   +1 more source

Demographic variation in symptoms of depression and anxiety across 22 Global Flourishing Study countries

Communications Medicine
Background We know relatively little about how mental health varies across countries around the world or among demographic groups in diverse nations and cultures.
Matt Bradshaw, Koichiro Shiba, Sung Joon Jang, Blake Victor Kent, Rebecca Bonhag, Byron R. Johnson, Tyler J. VanderWeele   +6 more
doaj   +1 more source

Ultrasonic‐Assisted Photocatalytic Conversion of Air to Nitric Acid Under Ambient Conditions

Advanced Science, EarlyView.
Ultrasound‐assisted photocatalytic air oxidation to nitrate enhances soil nitrogen fertilizer dynamics, thereby enabling improved energy conversion efficiency and sustainable agriculture. ABSTRACT The production of nitric acid (HNO3) holds significant importance in the chemical industry, and achieving direct air‐to‐HNO3 conversion with high efficiency ...
Shiming Chen, Hanlan Hong, Yunchuan Tu, Chao Zhen, Rui Zheng, Yuxi Yao, Junxiong Chen, Tianlin Wang, Xiumei Zhan, Fanhe Kong, Huazhe Yang, Gang Liu   +11 more
wiley   +1 more source

Integrating the humanities and the social sciences: six approaches and case studies

Humanities & Social Sciences Communications
The social sciences are still young, and their interaction with older siblings such as philosophy and theology is still necessarily tentative. This paper outlines three ways in which humanistic disciplines such as philosophy and theology might inform the
Brendan Case, Tyler J. VanderWeele
doaj   +1 more source

Harm and Money: Against the Insurance Theory of Tort Compensation [PDF]

, 1997
Since the 1980s, tort damages for pain and suffering have excited hue and cry. Twenty-three states currently place statutory limitations on tort damages for pain and suffering: seven states cap damages in general tort cases; an additional sixteen states ...
Feldman, Heidi Li
core   +1 more source

Compartmentalized Homeostasis Drives High Bamboo Forest Productivity under Nutrient Imbalance

Advanced Science, EarlyView.
This study reveals how Moso bamboo achieves high productivity despite nutrient‐poor soils. It employs a unique strategy, maintaining strict nutrient balance in its leaves while using woody tissues as flexible storage reservoirs. This compartmentalized mechanism buffers the plant from soil phosphorus limitation and microbial competition, resolving the ...
Zhikang Wang, Quan Li, Man Shi, Marcio F.A. Leite, Xinli Chen, Eiko E. Kuramae, Viviane Cordovez, Tingting Cao, Chenglei Zhu, Libin Zhou, Wenjuan Yu, Zhiyao Tang, Changhui Peng, Xinzhang Song   +13 more
wiley   +1 more source

Perspective: Hollow Core Optical Fibres for Ultraviolet and Visible Wavelengths

Advanced Science, EarlyView.
Hollow core optical fibres bypass material constraints that limit optical fibres at ultraviolet and visible wavelengths. However, their challenging fabrication has limited their development, and significant gains in performance remain possible. In this perspective we outline approaches to enable the next generation of fibres for shorter wavelengths ...
Robbie Mears, Kerrianne Harrington, Jonathan C. Knight, William J. Wadsworth, James M. Stone, Tim A. Birks   +5 more
wiley   +1 more source

Association between frailty and quality of life, and the moderating effect of mobile, broadcast and digital media in sub-Saharan Africa: evidence from Kenya

BMC Geriatrics
Background Globally, frailty is known to negatively impact quality of life, yet this relationship remains underexplored in Kenya. Additionally, there is growing interest in leveraging technology in health and social care to support vulnerable populations,
Gideon Dzando, Paul R. Ward, Lillian Mwanri, Richard K. Moussa, Rachel C. Ambagtsheer   +4 more
doaj   +1 more source

Microgel‐Based Hierarchical Porous Hydrogel Patch with Adhesion and Resilience for Myocardial Infarction

Advanced Science, EarlyView.
This study develops a hierarchically porous hydrogel patch strategy (HPMP), based on gas‐shearing microfluidics and an aqueous two‐phase system to fabricate porous microgels as microgel‐based bioinks. The porous microgels with controllable porous structure exhibit excellent cellular behavior.
Ziyang Liu, Leyan Xuan, Yingying Hou, Ting Xie, Jieting Li, Junjie Cai, Siyu Zhang, Yingling Miao, Ning Hou, Gen He, Maobin Xie, Xiyong Yu, Mingen Xu, Guosheng Tang   +13 more
wiley   +1 more source

Oral Celastrol Nanomedicine Targeting Intestinal Antigen‐Presenting Cells to Effectively Mitigate Autoimmune Uveitis via Gut‐Retina Axis

Advanced Science, EarlyView.
Oral nanoCEL exhibits effective intestinal targeting of antigen‐presenting cells and restores the Th17/Treg balance in lymph nodes and spleen, ultimately protecting the blood‐retinal barrier by inhibiting peripheral immune cell infiltration and suppressing retinal glial cell activation.
Jinrun Chen, Yuqin Wu, Bofei Xu, Jiabei Hou, Yijing Li, Yuhan Hu, Yutuo Zhu, Wenqiao Zhang, Shuqi Feng, Huanting Jin, Yuchen Cheng, Yuanyuan Jin, Jianhong Zhou, Xingyi Li   +13 more
wiley   +1 more source