Results 21 to 30 of about 650,345 (262)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa +3 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Flow-Injection Amperometric Determination of Ascorbic Acid Using a Graphite-Epoxy Composite Electrode Modified with Cobalt Phthalocyanine [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2001 A flow injection method is reported for the determination of ascorbic acid based on amperometric detection, using a cobalt(II) phthalocyanine (CoPc) modified graphite-epoxy electrode.
Jafar Hosseinalizadeh Khorasani +3 more
doaj
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Optimization of Flow Injection (FI) – Spectrophotometry for Hydroquinone Analysis [PDF]
Journal of Pure and Applied Chemistry Research, 2019 Hydroquinone is one of the phenolic compounds used in various cosmetic products for skin lightening as it can inhibit tyrosinase enzyme in producing melanin.
Muhammad Iqbal Fahmi +3 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Boron Doped Diamond Electrodes in Flow-Based Systems
Frontiers in Chemistry, 2019 Boron-doped diamond (BDD) electrodes present several notable properties, such as the largest potential window of all electrode materials (especially in anodic potentials), low background and capacitive currents, reduced fouling compared to other ...
Jhonys Machado Freitas +3 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Recent Electrochemical and Optical Sensors in Flow-Based Analysis
Sensors, 2006 Some recent analytical sensors based on electrochemical and optical detectioncoupled with different flow techniques have been chosen in this overview.
Nattakarn Wangfuengkanagul +4 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source