Results 91 to 100 of about 7,583,870 (302)

Statistical Analysis of High-Flow Traffic States

open access: yes, 2013
The relation between the fundamental observables of traffic flow (i.e., vehicle density, flow rate, and average velocity) is of great importance for the study of traffic phenomena. Probably the most common source of such data are inductive loop detectors,
Brügmann, Johannes   +3 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A Novel Membrane Sensor for Batch and Flow Injection Potentiometric Determination of Cefazolin Sodium in Pharmaceutical Preparations

open access: yesInternational Journal of Electrochemical Science, 2014
A novel potentiometric sensor was prepared, characterized and utilized for static and continuous determination of cefazolin sodium (CFZN). Several metal-ion complexes and anion exchangers were tested as electroactive materials in plasticized polymeric ...
Ibrahim H.A. Badr   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Unveiling Malicious Network Flows Using Benford’s Law

open access: yesMathematics
The increasing proliferation of cyber-attacks threatening the security of computer networks has driven the development of more effective methods for identifying malicious network flows.
Pedro Fernandes   +2 more
doaj   +1 more source

Why Does Flow Director Cause Packet Reordering?

open access: yes, 2011
Intel Ethernet Flow Director is an advanced network interface card (NIC) technology. It provides the benefits of parallel receive processing in multiprocessing environments and can automatically steer incoming network data to the same core on which its ...
Crawford, Matt, DeMar, Phil, Wu, Wenji
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Sistema de análises em fluxo polivalente para a determinação espectrofotométrica de fármacos

open access: yesQuímica Nova, 2011
A flow system based on the sandwich technique is proposed for the sequential determination of ascorbic acid, dipyrone, acetylcysteine, captopril and paracetamol.
Erlando Schmidt Jr   +2 more
doaj   +1 more source

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