Results 101 to 110 of about 7,583,870 (302)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

HPFTP flow diverter analysis [PDF]

A computational fluid flow analysis on the flow diverter system under consideration for the Space Shuttle main engine high pressure fuel turbopump (SSME HPFTP) is proposed.
Spadley, L. W.
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

COVID-19 Induced Changes in Residual Municipal Waste Management in Provincial Territories of the Marche Region (Italy): Flow Analysis and Environmental Assessment

Recycling
The COVID-19 pandemic posed challenges to pre-crisis waste management systems. In this study, two sequential scenarios were identified and compared to investigate the quantitative and environmental impacts of COVID-19 induced changes in the generation ...
Massimiliano Boccarossa, Lidia Lombardi, Fabio Tatàno, Adele Folino, Valentina Spadi, Francesca Tuci, Piero Sirini   +6 more
doaj   +1 more source

Object-based Control/Data-flow Analysis

, 2005
Not only does a clear distinction between control and data flow enhance the readability of models, but it also allows different tools to operate on the two distinct parts of the model.
Farwer, Berndt, Varea, Mauricio
core  

On the practicality of global flow analysis of logic programs [PDF]

, 1988
This paper addresses the issue of the practicality of global flow analysis in logic program compilation, in terms of both speed and precision of analysis.
Hermenegildo, Manuel V., Warren, Richard
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Analysis and Calculation of the Fluid Flow and the Temperature Field by Finite Element Modeling

Measurement Science Review, 2018
This paper presents a fundamental and accurate approach to study numerical analysis of fluid flow and heat transfer inside a channel. In this study, the Finite Element Method is used to analyze the channel, which is divided into small subsections.
Dhamodaran M., Jegadeesan S., Kumar R. Praveen   +2 more
doaj   +1 more source

Knowledge Flow Analysis for Security Protocols

, 2005
Knowledge flow analysis offers a simple and flexible way to find flaws in security protocols. A protocol is described by a collection of rules constraining the propagation of knowledge amongst principals. Because this characterization corresponds closely
Devadas, Srinivas, Gassend, Blaise, Jackson, Daniel, Torlak, Emina, van Dijk, Marten   +4 more
core   +1 more source