Results 61 to 70 of about 3,368,391 (285)
Quality assurance and e‐learning: blue skies and pragmatism [PDF]
, 2005 This paper considers the role of quality assurance in e‐learning; reflecting on the conditions necessary for successful e‐learning. It reviews some of the current international work on quality assurance in this area and goes on to consider the ways in ...
Oliver, Ron, Ron Oliver
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Applied SciencesInorganic scale formation in oil wells is a major flow assurance challenge, causing production losses, increased intervention costs and reduced operational efficiency.
Luila Abib Saidler +4 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
EnergiesGas hydrate formation in pipelines transporting multiphase fluids from petroleum reservoirs can lead to the formation of blockages, representing a significant flow assurance challenge.
Anqi Qu +6 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
CT&F Ciencia, Tecnología & Futuro, 2009 A thermodynamic structure has been modified in order to calculate cloud point, fluidity and amount of precipitated wax under a wide range of temperature conditions, composition, and high pressures.
Juan-Carlos-M Escobar-Remolina +2 more
doaj
ChemEngineeringCorrosion, salt deposition, and biofouling critically impair flow assurance and mechanical integrity in oil and gas production systems, resulting in escalating operating costs and environmental burdens.
Tatyana Semenova, Yan Koltsa
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source