Results 131 to 140 of about 2,034,998 (303)
Data-Driven Local Control Design for Active Distribution Grids Using Off-Line Optimal Power Flow and Machine Learning Techniques [PDF]
Stavros Karagiannopoulos +2 more
openalex +1 more source
Heuristic actuator selection with the use of data of nonlinear optimal control for fluid flows
Yasuo Sasaki, Taku Nonomura
openalex +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Object-based Control/Data-flow Analysis
Not only does a clear distinction between control and data flow enhance the readability of models, but it also allows different tools to operate on the two distinct parts of the model. This paper shows how the modelling based on control/data-flow analysis can benefit from an object-based approach.
Farwer, Berndt, Varea, Mauricio
openaire +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Flow Control of the Electric Fuel Pump for Unmanned Aerial Vehicle
Compared with the traditional fuel pump, electric fuel pump has the advantages of high reliability, high power density and fast response. Its accurate and rapid flow supply will effectively improve the flight performance of UAV, but its large-scale flow ...
XU Xingchen, FU Yaoming, AN Siqi
doaj
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source

