Results 211 to 220 of about 2,146,941 (285)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Construction and Validation of a Nomogram for Diagnosis of Female Stress Urinary Incontinence Combined with Anatomic/Intrinsic Urethral Sphincter Deficiency. [PDF]

Int J Womens Health
Hu G, Zhou L, Su W, Tang G, Zhao D, Tang J.   +5 more
europepmc   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Interpretable machine learning for predicting rating curve parameters using channel geometry and hydrological attributes across the United States. [PDF]

Sci Rep
Baruah A, Zarrabi R, Cohen S, Johnson JM, McDermott R.   +4 more
europepmc   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

Direct Methamphetamine Sensing in Flowing Wastewater via a 3D-Printed Flow-Through Cell. [PDF]

J Xenobiot
Svitková V, Horáková I, Kolivoška V, Vaněčková E, Dakošová O, Melníková E, Žabka D, Imreová Z, Tulipánová A, Drdanová AP, Haššo M, Nemeček P, Hatala M, Mackuľak T, Gál M.   +14 more
europepmc   +1 more source

[Aortic blood flow velocity curve. I. Normal blood flow curve].

Kardiologia polska, 1983
K, Loboz-Grudzień, L, Hirnlowa, J, Dyczyński, A, Kostecka-Pokryszko, L, Sokalski, R, Dutkiewicz   +5 more
openaire   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Performance Analysis of PEMFC with Non-Equidistant Depth 3D Flow Field. [PDF]

ACS Omega
Wu M, Gao M, Mao Z, Gao C, Sun Q, Gu Q, Chen A.   +6 more
europepmc   +1 more source

Structure Optimization of Polymerase Chain Reaction Devices Under High Flow Rate: A Numerical Study. [PDF]

Micromachines (Basel)
Zhou N, Han H, Fang L, Li S, Lei L.
europepmc   +1 more source