Results 51 to 60 of about 982,120 (265)

Analysis and Research on Jetting Ability of the Jet Dispensing Valve Driven by a Piezostack

工程科学与技术, 2013
:A new kind of jetting valve driven by the piezo-stack using its quick response and good output properties was presented.The jetting valve was comprised of piezo-stack,flexible lever beam,needle and nozzle.The force of adhesive when jetting was analyzed ...
焦晓阳, 刘建芳, 谷峰春, 刘国君, 刘晓论   +4 more
doaj  

Study on Dynamic Characteristics and Buffering Mechanisms of Drilling Pump Valve with Secondary Buffer Function

Actuators
This study addresses the impact-induced failure of drilling pump valves caused by uncontrolled disc–seat collisions by proposing a novel valve design incorporating a two-stage buffering mechanism.
Yi Wu, Yongjun Hou
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Microstructure and Mechanical Properties of Cu-CoatedCarbon-Nanotubes-Reinforced Aluminum Matrix Composites Fabricated by Ultrasonic-Assisted Casting

Metals
Carbon nanotubes (CNTs) are considered ideal nanoscale reinforcement for the development of high-performance metal matrix composites due to their unique structure and excellent mechanical properties.
Xiaojian Dong, Min Zeng, Hong Yan
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The resistance and flow field characteristics of moonpool and its improvement forms

Zhongguo Jianchuan Yanjiu, 2020
[Objectives] The moonpool is a type of opening structure through the hull from deck to bottom, but it often brings adverse impacts on the performance of resistance due to its complex flow.[Methods] The computational fluid dynamics(CFD) method was ...
ZHAN Xingyu, MAO Xiaofei
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Flow Field Modeling Analysis on Kitchen Environment with Air Conditioning Range Hood

Atmosphere
This study proposes a flow field modeling analysis of kitchen environments with air-conditioning range hoods. The substructure approach is applied to resolve the challenges of low computational efficiency and convergence difficulties associated with the ...
Xiaoying Huang, Zhihang Shen, Shunyu Zhang, Yongqiang Tan, Ang Li, Bingsong Yu, Yi Jiang, Liang Peng, Zhenlei Chen   +8 more
doaj   +1 more source

Effect of Vaneless Diffuser Shape on Performance of Centrifugal Compressor

Applied Sciences, 2020
The influence of four different vaneless diffuser shapes on the performance of centrifugal compressors is numerically studied in this paper. One of the studied shapes was a parallel wall diffuser. Two others had the width reduced only from hub and shroud
Qian Zhang, Qiuhong Huo, Lei Zhang, Lei Song, Jianmeng Yang   +4 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source