Results 111 to 120 of about 598,469 (307)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Numerical Studies on Flow Field Characteristics of Cavity Based Scramjet Combustors

open access: yes, 2013
The flow field within the combustor of scramjet engine is very complex and poses a considerable challenge in the design and development of a supersonic combustor with an optimized geometry.
Sivaraj Ponnusamy   +4 more
core   +1 more source

Design, Development and Performance Evaluation of Water-Lubricated Bearings with Diverse Groove Patterns: A CFD and Experimental Investigation

open access: yesModelling
Multi-grooved water-lubricated bearings (MGWLBs) are widely used in marine stern tube applications, where hydrodynamic performance is strongly influenced by groove geometry and operating conditions.
Khushal Nitin Rajvansh   +7 more
doaj   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Erosion of Liquid-solid Two-phase Flow on Eight-way Fracturing Head

open access: yesShiyou jixie, 2021
In order to explore the erosion wear law of high-pressure fluid on eight-way fracturing head, the physical model of eight-way fracturing head was built.
Bai Xiaonie   +5 more
doaj  

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Study on Wind Farm Flow Field Characteristics Based on Boundary Condition Optimization of Complex Mountain Numerical Simulation

open access: yes
The accurate prediction of the flow field characteristics of complex mountains is of great practical significance for the development and construction of wind farms, but it is not yet fully understood.
Mingjie Zhang   +11 more
core   +1 more source

Profound Leadership Strategies: Transcending the Leadership Crisis in the Age of Artificial Intelligence

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article examines the evolving role of organizational leadership amidst the rapid advancements in artificial intelligence (AI). It explores a broadly experienced and documented crisis in leadership, due in part to the disruptive nature of AI and emerging technology.
Rachel Wlodarsky, Davin Carr Chellman
wiley   +1 more source

VENTILATION AIR FLOW FIELD CHARACTERISTICS IN A HYDRO GENERATOR Model

open access: yes, 2016
Knowledge of the ventilation flow field characteristics in electric generators is crucial for both designing new generators and refurbishing old ones. Such knowledge is achievable by in-depth investigations of the aerodynamics in these machines.
Nilsson, Håkan   +3 more
core  

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi   +19 more
wiley   +1 more source

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