Results 51 to 60 of about 311,319 (263)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
PLoS ONE, 2015 Sprouting angiogenesis and capillary network formation are tissue scale phenomena. There are also sub-scale phenomena involved in angiogenesis including at the cellular and intracellular (molecular) scales.
Hossein Bazmara +5 more
doaj +1 more source
Flow Volume Loops in Patients With Goiters
Annals of Surgery, 1992 Plain radiology is the standard means of assessing upper airway obstruction in patients with goiters. Flow volume loop curves will provide additional information, because they allow a quantitative assessment of airflow dynamics in the respiratory cycle. Fifty-one patients had flow volume loops performed before and after thyroidectomy.
J G, Geraghty +3 more
openaire +3 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
A MULTIPHASE FLOW LOOP DESIGN FOR INVESTIGATING THE PARTIAL PHASE SEPARATION IN A PIPE TEE
Acta Polytechnica, 2019 This article presents a design and commissioning of a multiphase flow loop, which was developed for scrutinizing the partial phase separation characteristics of pipe Tees. Its length is 9m and its primary diameter is 0.078m (3 inches).
Ahmed Saieed +3 more
doaj +1 more source
A model of flow in a helium loop [PDF]
AIP Conference Proceedings, 2017 Naturally circulated helium loop is a device designed for a decay heat removal from fast nuclear reactors of the type ALLEGRO. The flow is provided by a potential energy difference between hot and cold piping branch. Here we introduce a 1D model of flow in the loop.
B. Knížat +5 more
openaire +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Spontaneous quantization of the Yang–Mills gradient flow
Nuclear Physics BWe formulate a nonsingular loop–space calculus for the Yang–Mills (YM) gradient flow directly in terms of Wilson loop functionals, rather than the underlying gauge fields.
Alexander Migdal
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Frontiers in Energy ResearchWith large-scale access to distributed new energy, the power flow form of the distribution network tends to be complex. The distribution loop network rate increases, resulting in serious circulation of the distribution network, which places significant ...
Zhu Liu +9 more
doaj +1 more source