Results 51 to 60 of about 308,569 (263)

Research on the minimum network loss optimization control strategy of the active distribution network based on the distributed power flow controller

Frontiers in Energy Research
With large-scale access to distributed new energy, the power flow form of the distribution network tends to be complex. The distribution loop network rate increases, resulting in serious circulation of the distribution network, which places significant ...
Zhu Liu, Jinfeng Wang, Guowei Guo, KangHeng Feng, Ximei Zhan, Fadong Peng, Dehuang Gong, Aihong Tang, Ma Lulu, Caili Xiang   +9 more
doaj   +1 more source

Solution of thixotropic model parameters during shutdown and restart of gelled crude oil in loop

You-qi chuyun, 2020
Thixotropy, an important index to measure the low-temperature fluidity of waxy crude oil, is crucial to the hydraulic characteristics and safety of gelled crude oil during pipeline shutdown and restart. In the existing process of solving the parameter of
Keping ZHAI, Xiuhua SHAN, Guozhong ZHANG, Gang LIU   +3 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Detecting and drilling in critical inclination window in slant wells by means of a two phase liquid-solid CFD model and experimental study

Kuwait Journal of Science, 2019
Build and hold from vertical section form slant wells. The hole cleaning phenomena in this wells can cause of many problems that increased the operational costs.
Mohsen Dehvedar, Parviz Moarefvand
doaj  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

The twisted gradient flow coupling at one loop

Journal of High Energy Physics, 2019
We compute the one-loop running of the SU(N) ’t Hooft coupof twelve-flavor SU(3) gauge theoryling in a finite volume gradient flow scheme using twisted boundary conditions.
Eduardo I. Bribián, Margarita García Pérez   +1 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

A Model for Inventory Control in Closed-Loop Supply Chain Management considering Multiple Objective Planning Case: Iran Khodro Cut and Press Shop Company [PDF]

Muṭāli̒āt-i Mudīriyyat-i Ṣan̒atī
Nowadays attending to closed-loop supply chain matter for survival in competitive circumstances not only has been become a controversial topic but also has been considered as a critical topic too.
Abolfazl Sadeghian, Seyed Mohammad Ali Khatami Firouzabadi, Laya Olfat, maghsoud Amiri   +3 more
doaj   +1 more source