Results 61 to 70 of about 4,171,981 (305)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

The Vital Role of Blood Flow-Induced Proliferation and Migration in Capillary Network Formation in a Multiscale Model of Angiogenesis.

open access: yesPLoS ONE, 2015
Sprouting angiogenesis and capillary network formation are tissue scale phenomena. There are also sub-scale phenomena involved in angiogenesis including at the cellular and intracellular (molecular) scales.
Hossein Bazmara   +5 more
doaj   +1 more source

Numerical assessment of stability behaviour in supercritical CO2 based NCLS configured with heater h

open access: yesJournal of Thermal Engineering, 2023
Three-dimensional numerical analysis is presented in this study to assess the transient and stability behaviour of supercritical CO2 (sCO2) based NCLs configured with three different types of heat sources, i.e., heater, a hot heat exchanger (HHX) and ...
Srivatsa THIMMAIAH   +3 more
doaj   +1 more source

Flow Volume Loops in Patients With Goiters

open access: yesAnnals of Surgery, 1992
Plain radiology is the standard means of assessing upper airway obstruction in patients with goiters. Flow volume loop curves will provide additional information, because they allow a quantitative assessment of airflow dynamics in the respiratory cycle. Fifty-one patients had flow volume loops performed before and after thyroidectomy.
J G, Geraghty   +3 more
openaire   +3 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Efficiency of Passive Open Loop Heat Removal Over Wide Range of Loop Flow Resistances – PASI Loop Tests in the EU-PASTELS Project [PDF]

open access: yes, 2023
The PASI test facility, designed and constructed at LUT University, is a model of a containment cooling system using an open passive heat removal loop.
Riikonen, Vesa   +4 more
core   +1 more source

A MULTIPHASE FLOW LOOP DESIGN FOR INVESTIGATING THE PARTIAL PHASE SEPARATION IN A PIPE TEE

open access: yesActa Polytechnica, 2019
This article presents a design and commissioning of a multiphase flow loop, which was developed for scrutinizing the partial phase separation characteristics of pipe Tees. Its length is 9m and its primary diameter is 0.078m (3 inches).
Ahmed Saieed   +3 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Decoupler Design for an Interacting Tanks System

open access: yesTikrit Journal of Engineering Sciences, 2008
The mathematical model for the two interacting tanks system was derived and the dynamic behavior of this system was studied by introducing a step change in inlet flow rate.
Duraid F. Ahmed
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

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