Results 51 to 60 of about 322,617 (263)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Research on the minimum network loss optimization control strategy of the active distribution network based on the distributed power flow controller

Frontiers in Energy Research
With large-scale access to distributed new energy, the power flow form of the distribution network tends to be complex. The distribution loop network rate increases, resulting in serious circulation of the distribution network, which places significant ...
Zhu Liu, Jinfeng Wang, Guowei Guo, KangHeng Feng, Ximei Zhan, Fadong Peng, Dehuang Gong, Aihong Tang, Ma Lulu, Caili Xiang   +9 more
doaj   +1 more source

Solution of thixotropic model parameters during shutdown and restart of gelled crude oil in loop

You-qi chuyun, 2020
Thixotropy, an important index to measure the low-temperature fluidity of waxy crude oil, is crucial to the hydraulic characteristics and safety of gelled crude oil during pipeline shutdown and restart. In the existing process of solving the parameter of
Keping ZHAI, Xiuhua SHAN, Guozhong ZHANG, Gang LIU   +3 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Closed parasitic flow loops and dominated loops in networks [PDF]

International Journal of Operational Research, 2019
The paper raises awareness of the presence of closed parasitic flow loops in the solutions of published algorithm for maximising the throughput flow in networks. If the rooted commodity is interchangeable commodity, a closed parasitic loop can effectively be present even if the routed commodity does not physically travel along a closed loop. The closed
openaire   +2 more sources

Detecting and drilling in critical inclination window in slant wells by means of a two phase liquid-solid CFD model and experimental study

Kuwait Journal of Science, 2019
Build and hold from vertical section form slant wells. The hole cleaning phenomena in this wells can cause of many problems that increased the operational costs.
Mohsen Dehvedar, Parviz Moarefvand
doaj  

Experimental Study of Flow-induced Pressure Fluctuations in Horizontal Straight Pipes with Single- and Two-phase Flow

한국해양공학회지
Pressure fluctuations caused by multiphase flow in piping systems can lead to structural vibration, noise generation, and potential damage to the piping infrastructure. This study examined flow-induced pressure fluctuations and their spatial distribution
Gang Nam Lee, Jae Hong Kim, Quang Khai Nguyen, Kuk-Su Kim, Kwang Hyo Jung   +4 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

The twisted gradient flow coupling at one loop

Journal of High Energy Physics, 2019
We compute the one-loop running of the SU(N) ’t Hooft coupof twelve-flavor SU(3) gauge theoryling in a finite volume gradient flow scheme using twisted boundary conditions.
Eduardo I. Bribián, Margarita García Pérez   +1 more
doaj   +1 more source