Results 71 to 80 of about 309,082 (262)
A Model for Inventory Control in Closed-Loop Supply Chain Management considering Multiple Objective Planning Case: Iran Khodro Cut and Press Shop Company [PDF]
Muṭāli̒āt-i Mudīriyyat-i Ṣan̒atīNowadays attending to closed-loop supply chain matter for survival in competitive circumstances not only has been become a controversial topic but also has been considered as a critical topic too.
Abolfazl Sadeghian +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
On the Dynamics of Open and Closed Loop Reverse Flow Catalytic Reactors
Chemical Engineering Transactions, 2013 In this paper the dynamics of a reverse flow catalytic reactor with and without control are compared and discussed. The control system acts on the inlet gas temperature. Depending on flow direction the temperature is measured at one specific point at the
A. Brasiello, S. Crescitelli, L. Russo
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
In Vitro Thrombogenicity Testing of Biomaterials in a Dynamic Flow Loop: Effects of Length and Quantity of Test Samples. [PDF]
J Med Device, 2023 Jamiolkowski MA +3 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Two-loop gradient-flow renormalization of scalar QCD
SciPost Physics CoreThe gradient-flow formalism is applied to a non-Abelian gauge theory with scalar and fermionic particles, dubbed "scalar QCD". It is shown that the flowed scalar quark requires a field renormalization, albeit only beyond the one-loop level.
Janosh Borgulat, Nils Felten, Robert V. Harlander, Jonas T. Kohnen
doaj +1 more source
Effect of Temperature on Thrombogenicity Testing of Biomaterials in an In Vitro Dynamic Flow Loop System. [PDF]
ASAIO J, 2023 Patel M +6 more
europepmc +1 more source