Results 21 to 30 of about 590,236 (268)

Impact of weirs in altering benthic macroinvertebrate assemblages and composition structure in the Luvuvhu River Catchment, South Africa

open access: yesFrontiers in Environmental Science
Stream flow weirs disrupt river flow regimes, physical conditions, and biological composition of rivers, posing significant threat to the river’s functionality, integrity, and sustainability.
Humbulani E. Munzhelele   +5 more
doaj   +1 more source

Modification of a recuperator construction with CFD methods

open access: yesChemical and Process Engineering, 2017
The purpose of the work was initial modification of the construction of a commercially produced heat exchanger – recuperator with CFD (computational fluid dynamics) methods, based on designs and process parameters which were provided.
Ludwig Wojciech, Zając Daniel
doaj   +1 more source

Numerical Simulation of High-Speed Non-equilibrium Flow with Applied Magnetic Field

open access: yesТруды Института системного программирования РАН, 2018
The paper describes the development and testing processes of a modification of an existing solver for hypersonic reacting flow within the OpenFOAM numerical simulation framework. The modification is suited to simulate the interaction between the flow and
A. I. Ryakhovskiy   +2 more
doaj   +1 more source

Performance Improvement of a Typical Manifold using Computational Fluid Dynamics

open access: yesMATEC Web of Conferences, 2016
This paper presents an analysis of fluid flow in a typical manifold. A commercially available Computational Fluid Dynamics (CFD) package has been used to analyze the flow pattern inside the manifold. Pressure drop in whole fluid domain and mass flow rate
Subaschandar N., Sakthivel G.
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman   +7 more
wiley   +1 more source

Chemical Modification of Insulin Using Flow Chemistry [PDF]

open access: yesChemBioChem
AbstractChemical modification of proteins is of growing importance to generate new molecular probes for chemical biology and for the development of new biopharmaceuticals. For example, two approved, long‐acting insulin variants are lipidated at the LysB29 side‐chain. Acylations of proteins have so far been performed in batch‐mode.
Haoyu Chen   +5 more
openaire   +3 more sources

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro   +11 more
wiley   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

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