Results 91 to 100 of about 973,831 (267)
It remains an open question how the hydrodynamics and morphology in sharp meander bends adapt to the changes in flow and sediment conditions induced by upstream damming.
Xin Liu +5 more
doaj +1 more source
A Review of Oscillators in Hydrokinetic Energy Harnessing Through Vortex-Induced Vibrations
This review investigates the role of vortex-induced vibrations (VIVs) in hydrokinetic energy harnessing, shedding light on their dual nature as both a challenge in offshore engineering and an untapped resource for renewable energy.
Deping Cao +14 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
This paper introduces a new tank design for dehydrating and desalting large volumes of crude oils previously degasified, crude oil dehydration efficiency is reduced by gas presence in the emulsion interphase.
Jorge-Enrique Forero +4 more
doaj
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Numerical Simulation of Flow Pattern on the Triangular Plan Form Weirs and Comparing to Linear weir Techniques Using Flow-3D [PDF]
Weirs have widely been used for the flood flow, flow measurement, flow diversion and control of water levels in dams, rivers and open channels. This study was curried out to investigate the hydraulic characteristics of flow over the sharp-crested ...
Amir Hamzeh Haghiabi +3 more
doaj
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source

