Results 151 to 160 of about 11,768,272 (311)

Shear flow patterns antimicrobial gradients across bacterial populations. [PDF]

Sci Adv
Shuppara AM, Padron GC, Sharma A, Modi Z, Koch MD, Sanfilippo JE.   +5 more
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Topology controls flow patterns in active double emulsions. [PDF]

Nat Commun
Negro G, Head LC, Carenza LN, Shendruk TN, Marenduzzo D, Gonnella G, Tiribocchi A.   +6 more
europepmc   +1 more source

Blood flow patterns switch VEGFR2 activity through differential S-nitrosylation and S-oxidation. [PDF]

Cell Rep, 2023
Kang DH, Kim Y, Min S, Lee SY, Chung KY, Baek IJ, Kwon K, Jo H, Kang SW.   +8 more
europepmc   +1 more source

Flows, Patterns and Topographies

Materia Arquitectura, 2011
Our lived landscapes are repositories of messages, of decisions taken by generations of cultural activity on the land. We can study the landscape to read our given world. But can we undertake this “landscape reading” in reverse, using its techniques to structure space, and “write” a way of living on the land The “Open City” of Ritoque has no urban ...
openaire   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Intrarenal venous flow patterns and their association with successful fluid removal in critically ill patients: a prospective observational exploratory study. [PDF]

Ultrasound J
Maluangnon C, Saokaew A, Rojwatcharapibarn S, Ratanarat R.   +3 more
europepmc   +1 more source

Flow patterns and morphology of a prograding river delta

, 2016
J. Shaw, D. Mohrig, R. Wagner
semanticscholar   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Evaluation of intrarenal vein flow patterns during routine echocardiography. [PDF]

Heart Vessels
Nagai T, Horinouchi H, Hirotsugu T, Ikari Y.   +3 more
europepmc   +1 more source