Results 211 to 220 of about 19,082,596 (312)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

The influence of hepatic arterial blood flow rate on holmium microsphere distribution: an MRI study in perfused porcine livers. [PDF]

Eur Radiol Exp
Snoeijink TJ, van den Brekel A, van der Hoek JL, Greve JGM, Remco Liefers H, Boswinkel M, Ruiter SJS, Roosen J, Jebbink EG, Nijsen JFW.   +9 more
europepmc   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Do fistula flow rate and fistula location have any effects on heart failure developing in patients with arteriovenous fistula? [PDF]

BMC Cardiovasc Disord
Yümün G, Donbaloğlu MO, Gürkan S, Gür Ö, Demirkıran A.   +4 more
europepmc   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Prolonged intermittent hemodialysis using a standard dialysate flow rate for severe overdose of sustained-release valproic acid: A case report. [PDF]

Toxicol Rep
Inoue H, Yoshikawa S, Matsukawa N, Shima A, Nishizawa T, Ueda T.   +5 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Impact of Gastroesophageal Reflux Disease on Salivary Flow Rate, pH and Buffer Capacity: A Systematic Review and Meta-Analysis. [PDF]

J Oral Rehabil
Hatipoğlu Ö, Yıldırım Ö, Hatipoğlu FP.   +2 more
europepmc   +1 more source

Human simulation model for predicting body temperature, blood pressure, and blood flow rate under various thermal exposures - Part 1: development of physical model for average Japanese male in their 20s. [PDF]

Int J Biometeorol
Goto T, Niu Z, Chiba Y, Amano K, Saijo Y.   +4 more
europepmc   +1 more source

Comparison of Two Coronary Anastomosis Techniques in Terms of Flow Rate in Porcine Hearts. [PDF]

Braz J Cardiovasc Surg
Gode S, Polat M, Guneysu E, Aksu T, Bayserke O, Bayram M, Kulacoglu UK, Iyigun T, Duman ZM, Inan O.   +9 more
europepmc   +1 more source