Results 21 to 30 of about 227,059 (254)

Spatial mapping reveals multi-step pattern of wound healing in Physarum polycephalum

, 2017
Wounding is a severe impairment of function, especially for an exposed organism like the network-forming true slime mould Physarum polycephalum. The tubular network making up the organism's body plan is entirely interconnected and shares a common ...
Alim, Karen, Bäuerle, Felix, Kramar, Mirna   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Nanomechanical single-photon routing [PDF]

, 2018
The merger between integrated photonics and quantum optics promises new opportunities within photonic quantum technology with the very significant progress on excellent photon-emitter interfaces and advanced optical circuits.
Liu, Zhe, Lodahl, Peter, Ludwig, Arne, Midolo, Leonardo, Papon, Camille, Schott, Rüdiger, Stobbe, Søren, Thyrrestrup, Henri, Wieck, Andreas D., Zhou, Xiaoyan   +9 more
core   +3 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

A droplet routing technique for fault-tolerant digital microfluidic devices [PDF]

, 2008
—Efficient droplet routing is one of the key approaches for realizing fault-tolerant microfluidic biochips. It requires that run-time diagnosis and fault recovery can be made possible in such systems.
Kerkhoff, Hans G., Proosdij, Frits van, Zhang, Xiao   +2 more
core   +3 more sources

Composite Electrospun Fibers Containing Optimized B‐ and Cu‐Doped Bioactive Glass Sol‐Gel Particles for Potential Soft Tissue Engineering Applications

Advanced Engineering Materials, EarlyView.
This article describes the preparation and characterization of poly(ε‐caprolactone) electrospun composite fibers incorporating sol‐gel‐derived bioactive glass particles doped with B and Cu. Scanning electron microscopy, energy‐dispersive X‐ray spectroscopy, Fourier‐transform infrared spectroscopy, contact angle, acellular bioactivity, mechanical and ...
Elisa Piatti, Marta Miola, Liliana Liverani, Paolo Sartori, Enrica Verné, Aldo R. Boccaccini   +5 more
wiley   +1 more source

High dimensionality carrierless amplitude phase modulation technique for radio over fiber system [PDF]

, 2017
Advanced modulation formats such as carrierless amplitude phase (CAP) modulation technique is one of the solutions to increase flexibility and high bit rates to support multi-level and multi-dimensional modulations with the absence of sinusoidal carrier.
Jaafar, Marliana
core  

Efficient Process Development for Laser Powder Bed Fusion of a Soft‐Magnetic Metallic Glass Composite

Advanced Engineering Materials, EarlyView.
Iron‐based metallic glass alloys exhibit excellent soft‐magnetic properties, and unprecedented geometrical freedom in the design of soft‐magnetic metallic glass components is made possible by additive manufacturing. An efficient workflow for developing parameters for laser‐based powder bed fusion of a Fe‐based metallic glass alloy is presented along ...
Julia Löfstrand, Priyanka Saha, Vidhiaza Leviandhika, Urban Wiklund, Alexander Elsen, Carolin Zintel, Lena Thorsson, Petra E. Jönsson   +7 more
wiley   +1 more source

Effects of Carbon Nanoparticles on Triboelectro‐Induced Surface Defects

Advanced Engineering Materials, EarlyView.
Carbon nanoparticles added to grease modify the electrocontact behavior. The synergy of particle concentration and electric current dominates the surface damage of metals in contact. Electrical surface damage caused by current leakage is a critical challenge in high‐performance applications such as electric vehicle (EV) drivetrains and wind turbine ...
Mohsen Tajedini, Lu Fang, Jacob Bons, Mohammad Humaun Kabir, Evan Johnson, Joe Kosmoski, Hong Liang   +6 more
wiley   +1 more source