Results 131 to 140 of about 3,286,488 (310)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A New Lower Bound for Flexible Flow Shop Problem with Unrelated Parallel Machines
International Journal of Industrial Engineering and Production Research, 2014 Flexible flow shop scheduling problem (FFS) with unrelated parallel machines contains sequencing in flow shop where, at any stage, there exists one or more processors. The objective consists of minimizing the maximum completion time.
Nasim Nahavandi, Ebrahim Asadi Gangraj
doaj
, 2023 Item 3642 contains images of Pyrmont, Harvey and Harris Streets, shell and gun annexe extension, gun shop, shell shop, tool room, pattern shop, heavy machine shop, fitting shop, boiler shop ...
Photographer: Unknown +1 more
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Time-window-based combined objective DE algorithm for hybrid flow-shop
, 2014 In this paper, a time-window-based hybrid flow-shop scheduling model is presented for manufacturing enterprise for solving production scheduling optimisation problem in the rolling production process. Time window deviation sum and the earliness/tardiness
Yao LL(姚丽丽) +2 more
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
A Branch-and-bound algorithm for n-job two-machine flow shop scheduling problems
, 1995 In this paper, we study the n-job two machine flow shop scheduling problem, minimizing the total job flow times. The problem is mathematically formulated, and two heuristic approaches are invented to find near optimum schedules.
Wang CE(王成恩) +2 more
core
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
New Shop Floor Control Approaches for Virtual Enterprises [PDF]
The virtual enterprise paradigm seems a fit response to face market instability and the volatile nature of business opportunities increasing enterprise’s interest in similar forms of networked organisations.
José Barata, Luís Ribeiro
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source