Results 61 to 70 of about 15,254 (266)

Solving resource-constrained construction scheduling problems with overlaps by metaheuristic

Journal of Civil Engineering and Management, 2014
The paper concerns the problem of roadworks scheduling executed in the flow-shop system. Works may be performed parallelly with the acceleration (overlaps) of construction project, i.e.
Wojciech Bożejko, Zdzisław Hejducki, Mariusz Uchroński, Mieczysław Wodecki   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

MODEL PENJADWALAN BACKWARD HYBRID FLOW SHOP 2 STAGE UNTUK MEMINIMASI MEAN FLOWTIME

Jurnal Lebesgue
The scheduling problem is a common challenge when it comes to executing tasks, making the resolution of this issue crucial for decision-making in production activities.
Asep Anwar, Rendiyatna Ferdian, Didit Damur Rochman   +2 more
doaj   +1 more source

Near-Optimal Heuristics for Just-In-Time Jobs Maximization in Flow Shop Scheduling

Algorithms, 2018
The number of just-in-time jobs maximization in a permutation flow shop scheduling problem is considered. A mixed integer linear programming model to represent the problem as well as solution approaches based on enumeration and constructive heuristics ...
Helio Yochihiro Fuchigami, Ruhul Sarker, Socorro Rangel   +2 more
doaj   +1 more source

A Note on Heuristics of Flow-Shop Scheduling [PDF]

Operations Research, 1996
We present an O(mn) two-group (TG) heuristic for the m-machine, n-job permutation flow-shop scheduling problem. We show that heuristic TG has a worst-case performance ratio of (m + 1)/2. We also establish worst-case bounds for several heuristics proposed in the past.
openaire   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Innovative Optimization Algorithms for Large-Sized Industrial Scheduling Problems [PDF]

Brazilian Archives of Biology and Technology
The problem of minimizing total quadratic completion time in flow shops presents a significant challenge in industries such as chemical, metallurgical, and ceramic manufacturing.
Helio Yochihiro Fuchigami, Alex Paranahyba Abreu   +1 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Workload Control in Flow Shops with Bottleneck Shifting and Process Time Variability

Production Engineering Archives
Manufacturing industries struggle to devise precise planning and scheduling solutions due to unpredictable business situations. Additionally, uncertainties in production such as machine breakdowns, labour absenteeism, cycle time deviations, etc., would ...
Prabhu Aruna, Raghunandana K, Pai P Yogesh   +2 more
doaj   +1 more source