Results 101 to 110 of about 161,061 (357)
Hierarchical Control of Production Flow based on Capacity Allocation for Real-Time Scheduling of Manufacturing System [PDF]
, 2009 8International audienceThis paper considers the modelling and simulation of a hierarchical production-flow control system. It uses a continuous control approach for machine capacity allocation at the design level and real time scheduling at the shop ...
Boukezzoula, Reda +2 more
core +1 more source
Climbing depth-bounded adjacent discrepancy search for solving hybrid flow shop scheduling problems with multiprocessor tasks [PDF]
, 2011 This paper considers multiprocessor task scheduling in a multistage hybrid flow-shop environment. The problem even in its simplest form is NP-hard in the strong sense.
A. Ben Hmida +13 more
core +2 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
International Journal of Production Management and Engineering, 2016 The flow-shop scheduling problem (FSP) has been widely studied in the literature and having a very active research area. Over the last few decades, a number of heuristic/meta-heuristic solution techniques have been developed.
Arun Gupta, Shailendra Kumar
doaj +1 more source
Scheduling of Flexible Manufacturing Systems using Intelligent heuristic search algorithm (IHSA*) [PDF]
, 2012 The complete scheduling of FMS includes two independent processes: sequencing of jobs and scheduling those prioritized jobs. In a flow shop or a Progressive type FMS, scheduling problem involves sequencing of ‘n’ jobs on ‘m’ machines with minimum ...
Gidhi, Pradyumna Kumar
core
Scheduling Jobs in Flowshops with the Introduction of Additional Machines in the Future [PDF]
, 2008 This is the author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by Elsevier and can be found at: http://www.journals.elsevier.com/expert-systems-with-applications/.The problem of scheduling jobs to ...
A. Apostolico +15 more
core +3 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
IET Collaborative Intelligent ManufacturingMatheuristic is an optimisation methodology that integrates mathematical approaches and heuristics to address intractable combinatorial optimisation problems, where a common framework is to insert mixed integer linear programming (MILP) models as local ...
Jiaxin Fan
doaj +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Advances in Mechanical Engineering, 2019 This article proposes a novel fuzzy model for solving fuzzy multi-objective permutation flow shop scheduling problem with fuzzy processing time. Specifically, two fuzzy objectives, that is, the fuzzy makespan and the fuzzy total flow time, are taken into
Fuyu Yuan, Xin Xu, Minghao Yin
doaj +1 more source