Results 81 to 90 of about 31,225 (293)
Experiments on fuel heating for commercial aircraft [PDF]
An experimental jet fuel with a -33 C freezing point was chilled in a wing tank simulator with superimposed fuel heating to improve low temperature flowability.
Friedman, R., Stockemer, F. J.
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Mechanical properties of native maize, wheat, and potato starches
Czech Journal of Food Sciences, 2013 The interrelations between moisture content and mechanical properties of dry and wet native starches of wheat, maize, and potato were investigated. Strength parameters of powders were tested using direct shear and ring shear tester.
Mateusz STASIAK +3 more
doaj +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
, 2016 For the purpose of applying laws or principles originated from thermal systems to granular athermal systems, we may need to properly define the critical temperature concept in granular powders.
Hao, Tian
core +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
PENGGUNAAN FLY ASH DAN VISCOCRETE PADA SELF COMPACTING CONCRETE
Civil Engineering Dimension, 2001 Self Compacting Concrete (SCC) gives a new solution in concrete technology, since SCC does not need vibrator for compacting. SCC has been used and developed abroad, however in Indonesia SCC is not used because there is no research about SCC yet.
Handoko Sugiharto, Gideon Hadi Kusuma
doaj
Chimica Techno ActaThe development of targeted drug delivery systems increasingly utilizes natural polymers like chitosan, prized for their biocompatibility and versatility.
Aleksandr A. Drannikov +9 more
doaj +1 more source
Cork-resin ablative insulation for complex surfaces and method for applying the same [PDF]
, 1980 A method of applying cork-resin ablative insulation material to complex curved surfaces is disclosed. The material is prepared by mixing finely divided cork with a B-stage curable thermosetting resin, forming the resulting mixture into a block, B-stage ...
Sharpe, M. H. +2 more
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source