Results 71 to 80 of about 15,542 (288)

Materials‐Guided Gene‐Ionizable Lipid Nanoparticles to Reverse Iron‐Associated Immune Resistance in Renal Cancer

Advanced Science, EarlyView.
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin, Yulong Hong, Chengliang Yin, Wanyang Guo, Yaxuan Wang, Ruijiang Zeng, Ruilin Liu, Zexian Ding, Xinlin Liu, Shangqing Ren, Qiyang Liang, Yaohui Wang, Xu Zhang, João Conde, Yuan Li, Xin Ma, Liangyou Gu   +16 more
wiley   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Evaluation of the Effects of Punica granatum Flower Tablets on Pain and Healing of Minor Recurrent Aphthous Stomatitis: A Randomized Clinical Trial

Clinical and Experimental Dental Research
Objectives The purpose of this study was to determine the therapeutic effect of the Punica granatum (PG) flower on recurrent aphthous stomatitis in comparison with corticosteroid therapy.
Fatemeh Lavaee, Elahehnaz Parhizkar, Fatemeh Tavakoli, Mohammad M. Zarshenas, Naeimehossadat Asmarian   +4 more
doaj   +1 more source

Flower-Like MnO₂ Nanoparticle-Based Dual GSH-Depleting Nanosystems for Chemo-/Chemodynamic/Sonodynamic Cancer Therapy

Chemodynamic therapy (CDT) generating hydroxyl radicals (•OH) by utilizing metal ions reacting with hydrogen peroxide (H2O2) is a highly encouraging strategy for cancer treatment.
Fang Zheng (54278), Xinrui Xue (18334510), Kun Wei (159944), Wenyu Chen (9135516), Yuanyuan Gao (448666), Chujie Xiao (18334513), Yujia Luo (18004582)   +6 more
core   +1 more source

A Piezo‐Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair

Advanced Science, EarlyView.
A piezo‐mimetic ionic hydrogel converts mechanical deformation into bioactive ionic currents via stress‐induced asymmetric ion migration. Coupled with sustained Mg2+ release, this mechano‐electrochemical platform bridges mechanical loading and cellular signaling, enabling load‐adaptive stimulation and enhanced cartilage regeneration. ABSTRACT Articular
Chenyuan Gao, Xinyu Wang, Zhifeng Wu, Xinya Zhang, Xiao Geng, Ti Zhang, Yue Wang, Hongwei Xia, Jun Zhang, Xianbo Qiu, Cuiru Sun, Yingjie Yu, Wenli Dai, Hua Tian, Qing Cai   +14 more
wiley   +1 more source

Asymmetrically Coordinated Dual‐Atom Manganese Contrast Agents Enabling High‐Efficiency T1 Enhanced MRI for Precise Tumor Visualization

Advanced Science, EarlyView.
A novel dual‐atom manganese MRI contrast agent (Mn‐BN) with a unique asymmetric coordination geometry provided a promising platform for sensitive and specific tumor imaging. In mice model, Mn‐BN nanoparticles precisely functioned as both a primary tumor‐specific enhancer in subcutaneous models and a hepatocyte‐specific agent in liver metastases models ...
Ding Yang, Qing‐Yang Li, Jianli Liang, Gengyou Li, Nan Sun, Qianqian Song, Haitao Zhu, Xiaoting Li, Zechuan Li, Jiankai Dong, Weisheng Guo, Yafang Xiao, Chun‐Sing Lee, Ying‐Shi Sun   +13 more
wiley   +1 more source

Application of floral therapy in patients with autoimmune diseases

Acta Médica del Centro, 2014
Invoked in the genesis and decompensated autoimmune diseases, stress, exhausted and overwhelmed when the person weakens its immune system, resulting in a failure of immune regulation or immunomodulation.
Lutgarda Pérez de Alejo Rodríguez, Lucia del Carmen Alba Pérez, Martha Pérez de Alejo Rodríguez, Carmen Xiomara Moré Chang, Dayami Rega Echeverría, Claristel Blanco Ramos   +5 more
doaj  

Trophic Diversity in Duckweed: Mixotrophy, More Than the Sum of its Extremes

Advanced Science, EarlyView.
In the context of rising DOC in aquatic environments, mixotrophic duckweed may impact carbon cycling by acting as either a carbon sink, as they absorb CO2 through photosynthesis, or a carbon source, as they release CO2 through respiration of absorbed DOC, which depends on DOC concentration, light availability, temperature, and other environmental ...
Zuoliang Sun, Yan Chen, Fajun Li, Xuyao Zhao, Qingxiang Han, Hongwei Hou   +5 more
wiley   +1 more source

ANALYSIS OF MENTAL NURSING CARE IN SCHIZOPHRENIC PATIENTS WITH THE APPLICATION OF OCCUPATIONAL THERAPY (SPARE TIME) TO OVERCOME LOW SELF-ESTEEM

Nurse and Holistic Care
Introduction: People with low self-esteem usually judge themselves negatively, feel guilty, feel useless, and feel insignificant. If this is not handled properly and quickly it will cause problems such as committing suicide, injuring others, and ...
Anugrah Lestari, Khamida, Syiddatul Budury, Erika Martining Wardani   +3 more
doaj   +1 more source

A Multimodal Magnetically Driven Soft Robot With Integrated Actuation‐Sensing Based on Photothermal Reprogramming Technology

Advanced Science, EarlyView.
This work reports a thermally safe, photothermally reprogrammable magnetic soft robot with its reprogramming temperature tuned to ∼39.5°C for biocompatibility. It achieves multimodal locomotion (max speed of 1.8 BL/s) and integrates liquid‐metal capacitive sensing to monitor self‐motion and detect environmental changes in simulated gastric environments,
Liu Yang, Yuliao Dong, Kangning Li, Cheng Jing, Ben Wang, Lin Xu   +5 more
wiley   +1 more source