Results 31 to 40 of about 121,424 (268)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Biology and Function of miR159 in Plants
MicroR159 (miR159) is ancient, being present in the majority of land plants where it targets a class of regulatory genes called GAMYB or GAMYB-like via highly conserved miR159-binding sites.
Anthony A. Millar +2 more
doaj +1 more source
I BEG to thank Mr. Perrycoste for his letter in NATURE of September 19. The county of Somerset has for some time had a by-law similar to that of the county of Cornwall; but you will observe that the by-law does not justify the protection of any particular plant, and that the special flora of Cheddar might easily disappear without any violation of its ...
openaire +2 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Ammonia thiosulfate in Japanese plum tree thinning [PDF]
In order to test the use of ammonia thiosulfate (ATS) in the chemical thinning of the Japanese plum tree, a field experiment was conducted throughout the 2015/2016 and 2016/2017 crop growing seasons at Ponta Grossa, PR, Brazil.
Ricardo Antonio Ayub +5 more
doaj +2 more sources
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Phenotyping crop performance is critical for line selection and variety development in plant breeding. Canola (Brassica napus L.) flowers, the bright yellow flowers, indeterminately increase over a protracted period.
Ti Zhang +6 more
doaj +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Flowering phenology of selected wind pollinated allergenic deciduous tree species
Systematic phenological observations have been carried out in the Dendrological Garden of August Cieszkowski Agricultural University, Park Sołacki, Lasek Golęciński, Przybyszewskiego Street, for two years (2003, 2004).
Magdalena Kluza-Wieloch, Joanna Szewczak
doaj +1 more source

