Results 51 to 60 of about 10,754,015 (243)
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
A genetic and molecular analysis of flowering time in Arabidopsis thaliana using natural variation = Een genetische en moleculaire analyse van bloeitijd in Arabidopsis thaliana gebruikmakend van natuurlijke variatie [PDF]
, 2002 The natural allelic variation at flowering time loci between two Arabidopsis thaliana accessions; Landsberg erecta (L er ) and the tropical Cape Verde Island (Cvi) has been analyzed.
El-Assal, S.E.D.
core
FLOWERING LOCUS T Regulates Stomatal Opening [PDF]
, 2011 SummaryStomatal pores surrounded by a pair of guard cells in the plant epidermis control gas exchange for photosynthesis in response to light, CO2, and phytohormone abscisic acid [1, 2].
Yuki Hayashi +21 more
core +1 more source
Frontiers in Plant ScienceFloral transition from the vegetative to the reproductive stages is precisely regulated by both environmental and endogenous signals. Among these signals, photoperiod is one of the most important environmental factors for onset of flowering.
Nayoung Lee +3 more
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Frontiers in Plant Science, 2017 Water deficit is a key factor to induce flowering in many woody plants, but reports on the molecular mechanisms of floral induction and flowering by water deficit are scarce.
Jin-Xue Li +11 more
doaj +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Plant responses to photoperiod [PDF]
, 2009 Photoperiod controls many developmental responses in animals, plants and even fungi. The response to photoperiod has evolved because daylength is a reliable indicator of the time of year, enabling developmental events to be scheduled to coincide with ...
Stephen D. Jackson, Jackson, Stephen D.
core +1 more source
FEBS Open Bio, EarlyView.The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
Potent induction of Arabidopsis thaliana flowering by elevated growth temperature. [PDF]
PLoS Genetics, 2006 The transition to flowering is an important event in the plant life cycle and is modulated by several environmental factors including photoperiod, light quality, vernalization, and growth temperature, as well as biotic and abiotic stresses.
Sureshkumar Balasubramanian +3 more
doaj +1 more source