Results 31 to 40 of about 576,757 (337)

Replication in human cells supersedes serum antigenic match for the in vivo efficacy of an A/H1N1pdm09 LAIV virus

npj Vaccines
For FluMist®/Fluenz live attenuated influenza vaccine (LAIV), efficient virus replication in human nasal epithelial cells (hNEC) is an important factor in vaccine effectiveness (VE).
Steffan Llewellyn, Katarzyna E. Schewe, Sameer Ayaz, David Burbidge, Shaun Cooper, Jonathan Crowe, Sarah Dodd, Jemma Shapanis, Katie Tudor, Kathryn Ryan, Lauren Parker, Oliver Dibben   +11 more
doaj   +1 more source

Fighting Flu Fatigue [PDF]

, 2010
Reviews responses to the 2009 H1N1 flu, including vaccination rates by state. Recommends steps to increase seasonal flu vaccination rates to boost preparations for flu pandemics and enhance prevention and response efforts for other health ...

core  

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Clinical pattern, diagnosis and treatment of flu and ARVI

Медицинский совет, 2015
Flu and ARVI are among the most dangerous infectious diseases recorded in Russia, both in terms of the financial burden and the damage they cause to the health of the population.
K. A. Aitov
doaj   +1 more source

Local skin reactions and the onset of influenza-like signs and symptoms induced by imiquimodCapsule Summary

JAAD International, 2022
Background: Since the introduction of imiquimod cream, patients have reported treatment-emergent symptoms that mimic influenza. However, clear relationships between the onset of symptoms from topical imiquimod and various variables (eg, patient’s age ...
Neal Bhatia, MD
doaj   +1 more source

H1N1 Challenges Ahead [PDF]

, 2009
Examines capacities and challenges in preparing for and responding to an H1N1 flu pandemic, including vaccine issues, confusion with seasonal flu, strain on medical systems, and erosion of public health infrastructure.

core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

SYMPTOMATIC THERAPY OF ACUTE RESPIRATORY INFECTIONS AND FLU IN CHILDREN

Медицинский совет, 2017
The article discusses approaches to therapy of acute respiratory infection (ARI) and flu. Some peculiarities of application of various non-steroid anti-inflammatory drugs in children are discussed.
V. A. Belov
doaj   +1 more source

Comparing the Attitude toward the COVID-19 and the 2020/21 and 2019/20 Flu Vaccination Campaigns among Italian Healthcare Workers

Vaccines, 2021
Background: While the uptake of the COVID-19 vaccine among healthcare workers (HCWs) is suboptimal, vaccine hesitancy has not been characterized in detail in this population.
Giulia Collatuzzo, Riccardo Melloni, Chiara Zanotti, Giulio de Simone, Danila Pilastro, Vittorio Lodi, Paolo Boffetta   +6 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source