Results 31 to 40 of about 249,961 (219)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Study of modal analysis based on fluid-structure interaction
Revista IBRACON de Estruturas e Materiais, 2018 In this work, a coupled fluid-structure problem is approached, comparing the result with the modal analysis of a structure. The objective of this work is to analyze the physical phenomenon of fluid-structure interaction of a flexible structure. For this,
M. PEGORARO, F. A. A. GOMES, P. R. NOVAK
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Low Reynolds Number Effect on Energy Extraction Performance of Semi-Passive Flapping Foil
Journal of Applied Fluid Mechanics, 2018 In this paper, 2-D numerical solution scheme is used to study the performance of semi-passive flapping foil flow energy harvester at Reynolds numbers ranging from 5000 to 50,000.
A. Javed, K. Djidjeli, J. T. Xing
doaj
Numerical simulation of fluid–structure interaction with SPH method
The Journal of Engineering, 2020 Smoothed particle hydrodynamics (SPH) is a meshfree, Lagrangian, particle method, which combines the advantages of Euler and Lagrangian method and has special advantages in simulating violent non-linear fluid–structure interaction problems. In this study,
Yu Yang, Jiaru Shao
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Applied and Computational Mechanics, 2017 A fixed point algorithmis proposed to solve a fluid-structure interaction problem with the supplementary constraint that the structure displacements are limited by a rigid obstacle.
Yakhlef O., Murea C.M.
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Simplified Aeroelastic Model for Fluid Structure Interaction between Microcantilever Sensors and Fluid Surroundings. [PDF]
PLoS ONE, 2015 Fluid-structural coupling occurs when microcantilever sensors vibrate in a fluid. Due to the complexity of the mechanical characteristics of microcantilevers and lack of high-precision microscopic mechanical testing instruments, effective methods for ...
Fei Wang +3 more
doaj +1 more source