Results 41 to 50 of about 604,004 (299)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Fluid-Structure Interaction In Mouth-Breathing Patients
International Dental JournalAim or purpose: This research uses the flow-solid coupling method to investigate the formation mechanism of mouth-breathing-related malformations. Materials and methods: This study developed a fluid-structure coupled finite element model of the upper ...
Wei Ji, Linkun Zhang, Yuan Luo
doaj +1 more source
Numerical simulation of fluid–structure interaction with SPH method
The Journal of Engineering, 2020 Smoothed particle hydrodynamics (SPH) is a meshfree, Lagrangian, particle method, which combines the advantages of Euler and Lagrangian method and has special advantages in simulating violent non-linear fluid–structure interaction problems. In this study,
Yu Yang, Jiaru Shao
doaj +1 more source
Partitioned algorithms for fluid-structure interaction problems in haemodynamics [PDF]
, 2012 We consider the fluid-structure interaction problem arising in haemodynamic applications. The finite elasticity equations for the vessel are written in Lagrangian form, while the Navier-Stokes equations for the blood in Arbitrary Lagrangian Eulerian ...
Vergara, Christian
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Fluid-Structure Interaction Mechanisms for Close-In Explosions
Shock and Vibration, 2000 This paper examines fluid-structure interaction for close-in internal and external underwater explosions. The resulting flow field is impacted by the interaction between the reflected explosion shock and the explosion bubble.
Andrew B. Wardlaw Jr., J. Alan Luton
doaj +1 more source
Computational Fluid-Structure Interaction Methods and Applications [PDF]
, 2013 reference for researchers and practicing engineers who would like to advance their existing knowledge on these subjects. It is also an ideal text for graduate and senior-level undergraduate courses in computational fluid mechanics and computational ...
Bazilevs, Yuri +2 more
core
A Fluid–Structure Interaction Algorithm Using Radial Basis Function Interpolation Between Non-Conforming Interfaces [PDF]
, 2016 We consider a fluid–structure interaction (FSI) problem discretized by finite elements featuring two different grids that do not necessarily agree on the interface separating the computational domain of the fluid from the one of the structure.
Forti, D. +8 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source