Results 221 to 230 of about 18,663 (284)

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

Effect of the Use of Electronic Media on the Cognitive Intelligence, Attention, and Academic Trajectory of Medical Students. [PDF]

Cureus
Hernández-Chávez A, Hamui-Sutton L, Muñoz-Comonfort A, Sampieri-Cabrera R.   +3 more
europepmc   +1 more source

Traceless Regulation of Genetic Circuitry

Advanced Science, EarlyView.
Energy‐based, as opposed to molecular, control offers unprecedented improvements in key circuit parameters. This review summarizes the fundamentals of such traceless switches, categorizes them by trigger modalities, and compares and contrasts distinct advantages as well as shortcomings of each kind.
Gokberk Unal, Martin Fussenegger
wiley   +1 more source

Understanding the Link Between Functional Profiles and Intelligence Through Dimensionality Reduction and Graph Analysis. [PDF]

Hum Brain Mapp
Alberti F, Menardi A, Margulies DS, Vallesi A.   +3 more
europepmc   +1 more source

The Effectiveness of the Maher Crystallized Intelligence Educational-Psychological Intervention on Enhancing Fluid Intelligence and Socio-Cultural Intelligence

Mohammad Hossein Zelli, Aboutaleb Seadatee Shamir, Ali Kazemi   +2 more
openalex   +2 more sources

Clarifying process versus structure in human intelligence: Stop talking about fluid and crystallized

, 2006
Wendy Johnson, Irving I. Gottesman
openalex   +2 more sources

Targeted Degradation of eEF2K by a Structure‐Guided PROTAC Strategy for the Treatment of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study developed an eEF2K‐targeting PROTAC, A6, that efficiently degrades eEF2K in TNBC cells, inhibiting tumor growth in vitro and in vivo. To enhance tumor‐specific delivery, we engineered A6@ZIF‐8, a pH‐sensitive nanocarrier, which improved drug accumulation at tumor sites, offering a promising therapeutic strategy for TNBC through targeted ...
Shijun Cao, Changxin Zhong, Shilong Jiang, Yungui Li, Yang Xi, Mingxuan Xiao, Ting Jiang, Xiaoya Wan, Zonglin Chen, Xiaohui Yu, Yan Cheng   +10 more
wiley   +1 more source

Developing brain asymmetry shapes cognitive and psychiatric outcomes in adolescence. [PDF]

Nat Commun
Wu X, Zhang K, Kuang N, Kong X, Cao M, Lian Z, Liu Y, Fan H, Yu G, Liu Z, Cheng W, Jia T, Sahakian BJ, Robbins TW, Feng J, Schumann G, Palaniyappan L, Zhang J.   +17 more
europepmc   +1 more source

Recent Advances in Laser‐Induced Graphene‐Based Gas Sensors: From Sensing Mechanisms to Biomedical Applications

Advanced Science, EarlyView.
Laser induced graphene offers a scalable route to flexible, porous gas sensor with tunable properties and self heating functionality. This summarizes the overview of the design and application landscape of LIG‐based wearable gas sensor in healthcare. ABSTRACT Direct laser irradiation of carbonaceous precursors such as polyimide and wood is a scalable ...
Md Abu Sayeed Biswas, Ankan Dutta, Shuvendu Das, Abu Musa Abdullah, Wanqing Zhang, Fatema Tuz Zohra, Huanyu Cheng   +6 more
wiley   +1 more source

Development and validation of the visual reasoning test for the NIH Toolbox. [PDF]

Psychol Assess
Slotkin J, Tyner CE, Ho EH, Kaat AJ, Dworak EM, Laforte E, Ma M, Han YC, Aytürk E, Zhang M, Tulsky DS, Gershon R.   +11 more
europepmc   +1 more source