Results 81 to 90 of about 1,811,844 (252)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

A New Solution of Drag for Newtonian Fluid Droplets in a Power-Law Fluid

open access: yesFluids
Understanding flow behaviors of multiple droplets in complex non-Newtonian fluids is crucial in many science and engineering applications. In this study, a new and improved analytical solution is developed based on the free surface cell model for the ...
Jianting Zhu
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Numerical simulation of the free convection in a viscous compressible fluid

open access: yesOpen Engineering, 2016
The numerical implementation of the classical model of thermal convection in a viscous compressible fluid in a finite domain is considered. Difference approximation carried out by the control volume method.
Perepechko Yury   +2 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Influence of a Given Field of Temperature on the Blood Pressure Variation: Variational Analysis, Numerical Algorithms and Simulations

open access: yesAxioms
This article presents a fluid–elastic structure interaction (FSI) problem when the temperature variation of the two media is also taken into account. We introduced the mathematical description of this interaction in a recent article.
Ruxandra Stavre, Alexandra Ciorogar
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Using the Lubrication Approximation to Model the Effects of Viscosity in DEM Simulations for Complex Flow Regimes

open access: yesKONA Powder and Particle Journal
This study explores an efficient approach to modelling the flow of particles in wet granular systems using the Discrete Element Method (DEM). Typically, when particles move in a viscous fluid, DEM is coupled with Computational Fluid Dynamics (CFD) or ...
David N. de Klerk   +3 more
doaj   +1 more source

Magnetohydrodynamic approximation of the complete equations for an electromagnetic fluid

open access: yesTsukuba Journal of Mathematics, 1986
The authors give a singular limit theorem for the magnetohydrodynamic equations in two space dimensions, which are obtained as the limit of the complete equations for the electromagnetic fluid at the vanishing of the dielectric constant. They show convergence of the solutions of the complete equations to the solutions of the magnetohydrodynamic ...
Kawashima, Shuichi, Shizuta, Yasushi
openaire   +5 more sources

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

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