Results 161 to 170 of about 1,534 (224)

Generalizing the Gaussian Network Model: Spanning‐Tree Thermodynamics Shows Entropy‐Driven KRAS Activation

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The GTPase KRAS executes a conformational switch between a GTP‐bound active state and a GDP‐bound inactive state, a process central to oncogenic signaling. However, the structural basis of this switching at the level of residue‐contact organization remains incompletely characterized by traditional binary structural models.
Fatma Senguler Ciftci, Burak Erman
wiley   +1 more source

Integrated evaluation and optimization of acid fracturing effectiveness in carbonate reservoirs: Experimental insights and field validation. [PDF]

PLoS One
Lu P, Li S, Liu J, Yuan N, Liu H.
europepmc   +1 more source

Analysis of C4 Concentrations to Predict Impact of Patient‐Reported Diarrhea Associated With the Ileal Bile Acid Transporter Inhibitor Linerixibat

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 596-605, March 2025.
ABSTRACT Linerixibat, an ileal bile acid transporter (IBAT) inhibitor, is being evaluated for the treatment of pruritus in primary biliary cholangitis (PBC). Diarrhea is commonly reported with this drug class as IBAT inhibition redirects bile acids (BA) to the colon.
Fernando Carreño, Rashmi Mehta, Andrea Ribeiro de Souza, Jon Collins, Brandon Swift   +4 more
wiley   +1 more source

Trichobezoar-induced intestinal obstruction-complete bowel obstruction in a young female with underlying psychiatric disorders: A case report. [PDF]

Int J Surg Case Rep
Bhatta BR, Manandhar K, Jha R, Duwal S, Shrestha S, Shrestha A.   +5 more
europepmc   +1 more source

Incorporation of Natural Antimicrobial Agents Into Thermoplastic Polymers for Food Applications: Strategies, Efficacy, Challenges and Future Directions

Packaging Technology and Science, EarlyView.
This graphical abstract summarizes the main strategies for incorporating natural antimicrobial agents into thermoplastic food packaging polymers, including melt processing, surface deposition, controlled release and chemical immobilization. It highlights the major classes of natural antimicrobials, key advantages such as microbial growth reduction and ...
Florence Akinmeye, Fabrice Gouanve, Fatima Zahra Jamal, Abdelkader Selmi, Sami Ghnimi   +4 more
wiley   +1 more source

Experimental study of microbial enhanced oil recovery in fractured porous media using the halophilic bacterium Haloferax mediterranei. [PDF]

Sci Rep
Eslam BZ, Hashemi R, Khaz'ali AR, Jazini M, Motlagh MAB.   +4 more
europepmc   +1 more source

Unmanned Aerial Systems for Corrosion Detection: Multi‐Sensor Technologies, Challenges, and Opportunities for Next‐Generation Inspection

Quality and Reliability Engineering International, EarlyView.
ABSTRACT Corrosion remains a critical threat to the integrity and service life of infrastructure in industries such as oil, gas, construction, renewable energy, and transportation. Traditional inspection methods, being labor‐intensive, hazardous, and often subjective, fall short in addressing modern inspection demands.
Alhossein Alharbi, Yunes Alqudsi, Alhasan Ali Alharbi, Mohammed Basheer Mohiuddin   +3 more
wiley   +1 more source

Development of an Intelligent Clinical Decision Support System for Spirometry Quality Control. [PDF]

Diagnostics (Basel)
López-Canay J, Priegue-Carrera A, Casado-Trigo A, Represas-Represas C, Fernández-García A, Comesaña-Campos A, Casal-Guisande M, Fernández-Villar A.   +7 more
europepmc   +1 more source

Baseline Neutrophil‐To‐Lymphocyte Ratio as a Risk Stratification Marker for Severe Checkpoint Inhibitor Pneumonitis in Patients With Non‐Small Cell Lung Cancer: A Two‐Cohort Study With Retrospective Discovery and Prospective Validation

Respirology, EarlyView.
The association between baseline neutrophil‐to‐lymphocyte ratio (NLR) and severe checkpoint inhibitor pneumonitis (CIP) was analyzed in discovery retrospective and validation prospective cohorts. Higher baseline NLR (≥ 4.75) was associated with increased severe CIP incidence in both cohorts.
Tetsu Hirakawa, Kakuhiro Yamaguchi, Shun Takao, Nobuhiro Kanaji, Naoko Matsumoto, Kozue Miyazaki, Tamio Okimoto, Chihiro Ando, Hisao Higo, Masaaki Yanai, Koji Kurose, Yasunari Nagasaki, Masako Watanabe, Kosuke Oyama, Yuko Toyoda, Yoshihiro Taguchi, Shimpei Tada, Kiyofumi Shimoji, Shinjiro Sakamoto, Yasushi Horimasu, Takeshi Masuda, Taku Nakashima, Hiroshi Iwamoto, Hironobu Hamada, Noboru Hattori   +24 more
wiley   +1 more source