Results 41 to 50 of about 2,983 (87)

Proximal pulmonary artery wall shear stress derived from computational fluid dynamics: A noninvasive biomarker for CTEPH and perfusion mismatch

Physiological Reports
Chronic thromboembolic pulmonary hypertension (CTEPH) is a severe complication of pulmonary embolism (PE), often diagnosed late due to nonspecific symptoms and limitations of current screening tools like V/Q scintigraphy.
Y. Bellouche, Cécile Tromeur, F. Le Ven, Philippe Robin, Christophe Gut-Gobert, P. Le Roux, Michel Nonent, A. Fauché, J. Elhasnaoui, Aurélia Le Hir, M. Guégan, Christophe Leroyer, P. Salaün, Bastien Pasdeloup, Romain Didier, Francis Couturaud   +15 more
semanticscholar   +1 more source

Data-driven Modeling of Parameterized Nonlinear Fluid Dynamical Systems with a Dynamics-embedded Conditional Generative Adversarial Network

arXiv.org
This work presents a data-driven solution to accurately predict parameterized nonlinear fluid dynamical systems using a dynamics-generator conditional GAN (Dyn-cGAN) as a surrogate model.
A. Rostamijavanani, Shanwu Li, Yongchao Yang   +2 more
semanticscholar   +1 more source

The generation and diffusion of vorticity in three-dimensional flows: Lyman's flux

Journal of Fluid Mechanics, 2021
We examine Lyman's (Appl. Mech. Rev., vol. 43, issue 8, 1990, pp. 157–158) proposed definition of the boundary vorticity flux, as an alternative to the traditional definition provided by Lighthill (Introduction: boundary layer theory. In Laminar Boundary
S. Terrington, K. Hourigan, M. Thompson
semanticscholar   +1 more source

Effects of fluid shear stress duration on the mechanical properties of HeLa cells using atomic force microscopy

PLoS ONE
Cellular mechanical properties play a critical role in physiological and pathological processes, with fluid shear stress being a key determinant. Despite its importance, the impact of fluid shear stress on the mechanical characteristics of HeLa cells and
Xinyao Zhao, Xiaolong Zhang, Fei Lei, Weikang Guo, Hui Yu, Yaoxian Wang   +5 more
semanticscholar   +1 more source

Fluid Flow Analysis of Pulmonary Hypertension in End Stage Renal Disease: A NAMS-Driven Case Study.

Journal of Biomechanical Engineering
Pulmonary hypertension (PH) is a serious condition affecting patients with end-stage renal disease (ESRD), yet the hemodynamic mechanisms underlying development remain poorly understood.
Fatemeh Bahmani, Daniel Pearce, Kaitlin Southern, Kenechukwu Nwadiaro, Veeranna Maddipatiti, Stephanie M George   +5 more
semanticscholar   +1 more source

Development of a Custom Fluid Flow Chamber for Investigating the Effects of Shear Stress on Periodontal Ligament Cells

Cells
The periodontal ligament (PDL) is crucial for maintaining the integrity and functionality of tooth-supporting structures. Mechanical forces applied to the tooth during orthodontic tooth movement generate pore pressure gradients, leading to interstitial ...
Mustafa Nile, Matthias Folwaczny, Andreas Kessler, Andrea Wichelhaus, Mila Janjić Ranković, U. Baumert   +5 more
semanticscholar   +1 more source

Local Well-Posedness of a System Coupling Compressible Atmospheric Dynamics and a Microphysics Model of Moisture in Air

SIAM Journal on Mathematical Analysis
We establish here the local-in-time well-posedness of strong solutions with large initial data to a system coupling compressible atmospheric dynamics with a refined moisture model introduced in Hittmeir and Klein (Theor. Comput. Fluid Dyn.
Sabine Doppler, Rupert Klein, Xin Liu, E. Titi   +3 more
semanticscholar   +1 more source

The role of fluid flow patterns in microbubble-mediated endothelial cell membrane permeabilization

Journal of the Acoustical Society of America
Blood flow dynamics vary throughout the circulatory system, influencing the pathophysiology of vascular endothelium. We investigated endothelial cell response to ultrasound-stimulated microbubbles across diverse anatomical sites by mimicking assorted ...
Elahe Memari, Brandon Helfield
semanticscholar   +1 more source

Stochastic Lagrangian dynamics of vorticity. Part 1. General theory for viscous, incompressible fluids

Journal of Fluid Mechanics, 2020
Prior mathematical work of Constantin & Iyer (Commun. Pure Appl. Maths, vol. 61, 2008, pp. 330–345; Ann. Appl. Probab., vol. 21, 2011, pp. 1466–1492) has shown that incompressible Navier–Stokes solutions possess infinitely many stochastic Lagrangian ...
G. Eyink, Akshat Gupta, T. Zaki
semanticscholar   +1 more source

NLRP3 inflammasome activation by turbulent shear stress drives right ventricular outflow tract fibrosis in pulmonary regurgitation

Frontiers in Cardiovascular Medicine
Objective This study aimed to investigate the role of turbulent shear stress (TSS) induced by pulmonary regurgitation (PR) in driving right ventricular (RV) dysfunction, with a focus on NLRP3 inflammasome activation, inflammation, and fibrosis ...
Qiang Fan, Yabo Wang, Dongyong Zhu, Qi An, Yunfei Ling   +4 more
semanticscholar   +1 more source